jefferson1 Posted January 22 Report Posted January 22 32 minutes ago, BulletBaskar said: indomethacin bro was this recommended buy india doctor or US doctor Quote
Silent_Boy Posted January 23 Report Posted January 23 4 hours ago, BulletBaskar said: allopurinol 300 mg 100 mg here. Bro dont take indomethacin regularly. Buy this or similar to it. very useful when you do workout or activities. https://www.amazon.com/dp/B0CHFJB1FZ?ref=ppx_yo2ov_dt_b_fed_asin_title&th=1 1 Quote
gothamprince Posted January 23 Report Posted January 23 7 hours ago, BulletBaskar said: hello guys need your suggestions. I have high uric acid levels (9.5 undi naaku instead of max 7.2) tablets eskuntunna. 2 weeks back doctor daggara poina...anti inflamatory tablets ichindi....taggindi.... Yearly checkups lo they said no issue with thyroid, kidney, etc etc mandhu manesa for 3 weeks mukka kuda tinaledu (only chicken 2 times tinnanu in 3 weeks) regular ga 3-4 times badminton aadutha in a week. gym ki 2 days potha in a week malli gout ochindi ivala.....jeevitham mida virakti ostundi ofcourse doctor daggara potha repo ellundo.....but any good suggestions from you guys? I will explain it clearly forget whatever everyone said, I am a doctor so follow this explanation carefully Gout is due to excess of uric acid when sufficient PH is met is deposited as uric acid crystals in the joints Uric acid is produced from purine metabolism only 1/3rd of the purines in the body is from dietary source approximately 400mg/24 hours and 2/3rd is derived from body own metabolism mostly during recycling of RNA and DNA in our body which is approximately 800mg/24hours, so now you can understand by this diet is not the major factor ,the major factor is your body producing uric acid , some may produce more uric acid due to mutations which are not fully understood but one such condition is inherited condition called lesch nyhan syndrome Now coming to excretion of uric acid 2/3rd of it is excreted in urine that is 800mg/ day and 1/3rd through stools appx 400mg/day Some of the mutations can also cause increased reabsorbtion of uric acid back into the body through kidneys So for increase in uric acid levels the problem can be any where in above mentioned processes In over 90% of cases the cause of increased uric acid in the body is reduced uric acid excretion by kidneys which is genetically determined So from all this you can understand the only thing in your hand is diet control but this is not a major contributing factor of the problem So reduce the intake of purine rich foods such as sea foods, red meat and fructose rich foods such as processed bakery items and soft drinks should be limited and alcohol especially beer should be avoided and reduction of weight is also suggested by regular exercise and increase the intake of vitamin c rich foods such as citrus fruits Disclaimer don't except any drastic change in improvement after dietary changes as uric acid is already deposited in your joints Now coming to the most important part the pharmacological treatment During gout episode we usually give colchicine 0.5mg twice or thrice daily ,oral NSAIDS like indomethacin can also be given but we prefer colchicine here The drug you are taking is allopurinol which increases the excretion of uric acid in the urine should not be given during the period of the gout flare but after the episode subsides to prevent the recurrence so should not be given during initial episode , we start with initial dose of 100mg daily Allopurinol initially causes dissolution of uric acid crystals already deposited so it temporarily causes increase of uric acid levels in the body so initially after start of treatment of allopurinol you get more flareups of gout but gradually the uric acid levels will stabilise and episodes will reduce so stay strong and also the initial dose in your case is 300mg which is high in my view so your fluctuations of uric acid is more than expected so more gout flare, so be patient it will work The dose of allopurinol can be increased by 100mg every 4 weeks until the uric acid levels in the body stabilises After all this if there is no sufficient improvement then there is febuxostat which can replace allopurinol Don't stress too much on dietary changes , but try as much possible, highly restrictive diet not necessary Hope this helps, I know it's difficult now but stay strong the condition will improve but remember this is long term battle @pichhipullayya how is the explanation, satisfied 😂 2 Quote
gothamprince Posted January 23 Report Posted January 23 Just now, gothamprince said: I will explain it clearly forget whatever everyone said, I am a doctor so follow this explanation carefully Gout is due to excess of uric acid when sufficient PH is met is deposited as uric acid crystals in the joints Uric acid is produced from purine metabolism only 1/3rd of the purines in the body is from dietary source approximately 400mg/24 hours and 2/3rd is derived from body own metabolism mostly during recycling of RNA and DNA in our body which is approximately 800mg/24hours, so now you can understand by this diet is not the major factor ,the major factor is your body producing uric acid , some may produce more uric acid due to mutations which are not fully understood but one such condition is inherited condition called lesch nyhan syndrome Now coming to excretion of uric acid 2/3rd of it is excreted in urine that is 800mg/ day and 1/3rd through stools appx 400mg/day Some of the mutations can also cause increased reabsorbtion of uric acid back into the body through kidneys So for increase in uric acid levels the problem can be any where in above mentioned processes In over 90% of cases the cause of increased uric acid in the body is reduced uric acid excretion by kidneys which is genetically determined So from all this you can understand the only thing in your hand is diet control but this is not a major contributing factor of the problem So reduce the intake of purine rich foods such as sea foods, red meat and fructose rich foods such as processed bakery items and soft drinks should be limited and alcohol especially beer should be avoided and reduction of weight is also suggested by regular exercise and increase the intake of vitamin c rich foods such as citrus fruits Disclaimer don't except any drastic change in improvement after dietary changes as uric acid is already deposited in your joints Now coming to the most important part the pharmacological treatment During gout episode we usually give colchicine 0.5mg twice or thrice daily ,oral NSAIDS like indomethacin can also be given but we prefer colchicine here The drug you are taking is allopurinol which increases the excretion of uric acid in the urine should not be given during the period of the gout flare but after the episode subsides to prevent the recurrence so should not be given during initial episode , we start with initial dose of 100mg daily Allopurinol initially causes dissolution of uric acid crystals already deposited so it temporarily causes increase of uric acid levels in the body so initially after start of treatment of allopurinol you get more flareups of gout but gradually the uric acid levels will stabilise and episodes will reduce so stay strong and also the initial dose in your case is 300mg which is high in my view so your fluctuations of uric acid is more than expected so more gout flare, so be patient it will work The dose of allopurinol can be increased by 100mg every 4 weeks until the uric acid levels in the body stabilises After all this if there is no sufficient improvement then there is febuxostat which can replace allopurinol Don't stress too much on dietary changes , but try as much possible, highly restrictive diet not necessary Hope this helps, I know it's difficult now but stay strong the condition will improve but remember this is long term battle @pichhipullayya how is the explanation, satisfied 😂 @pichhipullayya @johnydanylee and all members of this db you can ask me anything related your health related queries, never hesitate In return na Trisha thread ni lepali roi or atleast one health advice ki one Trisha pic veyyali or atleast nenu frustration Edo Trisha pics vesukuntunte nannu mingakandi, this is bare minimum 😂 2 Quote
gothamprince Posted January 23 Report Posted January 23 6 minutes ago, gothamprince said: I will explain it clearly forget whatever everyone said, I am a doctor so follow this explanation carefully Gout is due to excess of uric acid when sufficient PH is met is deposited as uric acid crystals in the joints Uric acid is produced from purine metabolism only 1/3rd of the purines in the body is from dietary source approximately 400mg/24 hours and 2/3rd is derived from body own metabolism mostly during recycling of RNA and DNA in our body which is approximately 800mg/24hours, so now you can understand by this diet is not the major factor ,the major factor is your body producing uric acid , some may produce more uric acid due to mutations which are not fully understood but one such condition is inherited condition called lesch nyhan syndrome Now coming to excretion of uric acid 2/3rd of it is excreted in urine that is 800mg/ day and 1/3rd through stools appx 400mg/day Some of the mutations can also cause increased reabsorbtion of uric acid back into the body through kidneys So for increase in uric acid levels the problem can be any where in above mentioned processes In over 90% of cases the cause of increased uric acid in the body is reduced uric acid excretion by kidneys which is genetically determined So from all this you can understand the only thing in your hand is diet control but this is not a major contributing factor of the problem So reduce the intake of purine rich foods such as sea foods, red meat and fructose rich foods such as processed bakery items and soft drinks should be limited and alcohol especially beer should be avoided and reduction of weight is also suggested by regular exercise and increase the intake of vitamin c rich foods such as citrus fruits Disclaimer don't except any drastic change in improvement after dietary changes as uric acid is already deposited in your joints Now coming to the most important part the pharmacological treatment During gout episode we usually give colchicine 0.5mg twice or thrice daily ,oral NSAIDS like indomethacin can also be given but we prefer colchicine here The drug you are taking is allopurinol which increases the excretion of uric acid in the urine should not be given during the period of the gout flare but after the episode subsides to prevent the recurrence so should not be given during initial episode , we start with initial dose of 100mg daily Allopurinol initially causes dissolution of uric acid crystals already deposited so it temporarily causes increase of uric acid levels in the body so initially after start of treatment of allopurinol you get more flareups of gout but gradually the uric acid levels will stabilise and episodes will reduce so stay strong and also the initial dose in your case is 300mg which is high in my view so your fluctuations of uric acid is more than expected so more gout flare, so be patient it will work The dose of allopurinol can be increased by 100mg every 4 weeks until the uric acid levels in the body stabilises After all this if there is no sufficient improvement then there is febuxostat which can replace allopurinol Don't stress too much on dietary changes , but try as much possible, highly restrictive diet not necessary Hope this helps, I know it's difficult now but stay strong the condition will improve but remember this is long term battle @pichhipullayya how is the explanation, satisfied 😂 @pichhipullayya is it possible to pin this comment so everyone can see it and may help them , intha essay nenu na exams lo kuda Rayaledu nanna chala detail ga explain cheyadaniki try chesa Quote
gothamprince Posted January 23 Report Posted January 23 30 minutes ago, gothamprince said: I will explain it clearly forget whatever everyone said, I am a doctor so follow this explanation carefully Gout is due to excess of uric acid when sufficient PH is met is deposited as uric acid crystals in the joints Uric acid is produced from purine metabolism only 1/3rd of the purines in the body is from dietary source approximately 400mg/24 hours and 2/3rd is derived from body own metabolism mostly during recycling of RNA and DNA in our body which is approximately 800mg/24hours, so now you can understand by this diet is not the major factor ,the major factor is your body producing uric acid , some may produce more uric acid due to mutations which are not fully understood but one such condition is inherited condition called lesch nyhan syndrome Now coming to excretion of uric acid 2/3rd of it is excreted in urine that is 800mg/ day and 1/3rd through stools appx 400mg/day Some of the mutations can also cause increased reabsorbtion of uric acid back into the body through kidneys So for increase in uric acid levels the problem can be any where in above mentioned processes In over 90% of cases the cause of increased uric acid in the body is reduced uric acid excretion by kidneys which is genetically determined So from all this you can understand the only thing in your hand is diet control but this is not a major contributing factor of the problem So reduce the intake of purine rich foods such as sea foods, red meat and fructose rich foods such as processed bakery items and soft drinks should be limited and alcohol especially beer should be avoided and reduction of weight is also suggested by regular exercise and increase the intake of vitamin c rich foods such as citrus fruits Disclaimer don't except any drastic change in improvement after dietary changes as uric acid is already deposited in your joints Now coming to the most important part the pharmacological treatment During gout episode we usually give colchicine 0.5mg twice or thrice daily ,oral NSAIDS like indomethacin can also be given but we prefer colchicine here The drug you are taking is allopurinol which increases the excretion of uric acid in the urine should not be given during the period of the gout flare but after the episode subsides to prevent the recurrence so should not be given during initial episode , we start with initial dose of 100mg daily Allopurinol initially causes dissolution of uric acid crystals already deposited so it temporarily causes increase of uric acid levels in the body so initially after start of treatment of allopurinol you get more flareups of gout but gradually the uric acid levels will stabilise and episodes will reduce so stay strong and also the initial dose in your case is 300mg which is high in my view so your fluctuations of uric acid is more than expected so more gout flare, so be patient it will work The dose of allopurinol can be increased by 100mg every 4 weeks until the uric acid levels in the body stabilises After all this if there is no sufficient improvement then there is febuxostat which can replace allopurinol Don't stress too much on dietary changes , but try as much possible, highly restrictive diet not necessary Hope this helps, I know it's difficult now but stay strong the condition will improve but remember this is long term battle @pichhipullayya how is the explanation, satisfied 😂 @jefferson1 this may help you too Quote
BulletBaskar Posted January 23 Author Report Posted January 23 4 hours ago, jefferson1 said: was this recommended buy india doctor or US doctor nen oka question adigithe nuvve nannu padi prashnalu adugutunnav?? endi va nuvu Quote
pichhipullayya Posted January 23 Report Posted January 23 37 minutes ago, gothamprince said: @pichhipullayya is it possible to pin this comment so everyone can see it and may help them , intha essay nenu na exams lo kuda Rayaledu nanna chala detail ga explain cheyadaniki try chesa @psycopk please do the needful. Quote
BulletBaskar Posted January 23 Author Report Posted January 23 50 minutes ago, gothamprince said: I will explain it clearly forget whatever everyone said, I am a doctor so follow this explanation carefully Gout is due to excess of uric acid when sufficient PH is met is deposited as uric acid crystals in the joints Uric acid is produced from purine metabolism only 1/3rd of the purines in the body is from dietary source approximately 400mg/24 hours and 2/3rd is derived from body own metabolism mostly during recycling of RNA and DNA in our body which is approximately 800mg/24hours, so now you can understand by this diet is not the major factor ,the major factor is your body producing uric acid , some may produce more uric acid due to mutations which are not fully understood but one such condition is inherited condition called lesch nyhan syndrome Now coming to excretion of uric acid 2/3rd of it is excreted in urine that is 800mg/ day and 1/3rd through stools appx 400mg/day Some of the mutations can also cause increased reabsorbtion of uric acid back into the body through kidneys So for increase in uric acid levels the problem can be any where in above mentioned processes In over 90% of cases the cause of increased uric acid in the body is reduced uric acid excretion by kidneys which is genetically determined So from all this you can understand the only thing in your hand is diet control but this is not a major contributing factor of the problem So reduce the intake of purine rich foods such as sea foods, red meat and fructose rich foods such as processed bakery items and soft drinks should be limited and alcohol especially beer should be avoided and reduction of weight is also suggested by regular exercise and increase the intake of vitamin c rich foods such as citrus fruits Disclaimer don't except any drastic change in improvement after dietary changes as uric acid is already deposited in your joints Now coming to the most important part the pharmacological treatment During gout episode we usually give colchicine 0.5mg twice or thrice daily ,oral NSAIDS like indomethacin can also be given but we prefer colchicine here The drug you are taking is allopurinol which increases the excretion of uric acid in the urine should not be given during the period of the gout flare but after the episode subsides to prevent the recurrence so should not be given during initial episode , we start with initial dose of 100mg daily Allopurinol initially causes dissolution of uric acid crystals already deposited so it temporarily causes increase of uric acid levels in the body so initially after start of treatment of allopurinol you get more flareups of gout but gradually the uric acid levels will stabilise and episodes will reduce so stay strong and also the initial dose in your case is 300mg which is high in my view so your fluctuations of uric acid is more than expected so more gout flare, so be patient it will work The dose of allopurinol can be increased by 100mg every 4 weeks until the uric acid levels in the body stabilises After all this if there is no sufficient improvement then there is febuxostat which can replace allopurinol Don't stress too much on dietary changes , but try as much possible, highly restrictive diet not necessary Hope this helps, I know it's difficult now but stay strong the condition will improve but remember this is long term battle @pichhipullayya how is the explanation, satisfied 😂 thanks bro thanks for the detailed explanation 1 Quote
jefferson1 Posted January 23 Report Posted January 23 21 minutes ago, gothamprince said: @jefferson1 this may help you too thank you i am taking one allo 100mg tablet every day its around 5 now. can i bring it down more as it is a good idea? 6 minutes ago, BulletBaskar said: nen oka question adigithe nuvve nannu padi prashnalu adugutunnav?? endi va nuvu going through same problem as you 1 Quote
Popular Post Express_Raja Posted January 23 Popular Post Report Posted January 23 1 hour ago, gothamprince said: I will explain it clearly forget whatever everyone said, I am a doctor so follow this explanation carefully Gout is due to excess of uric acid when sufficient PH is met is deposited as uric acid crystals in the joints Uric acid is produced from purine metabolism only 1/3rd of the purines in the body is from dietary source approximately 400mg/24 hours and 2/3rd is derived from body own metabolism mostly during recycling of RNA and DNA in our body which is approximately 800mg/24hours, so now you can understand by this diet is not the major factor ,the major factor is your body producing uric acid , some may produce more uric acid due to mutations which are not fully understood but one such condition is inherited condition called lesch nyhan syndrome Now coming to excretion of uric acid 2/3rd of it is excreted in urine that is 800mg/ day and 1/3rd through stools appx 400mg/day Some of the mutations can also cause increased reabsorbtion of uric acid back into the body through kidneys So for increase in uric acid levels the problem can be any where in above mentioned processes In over 90% of cases the cause of increased uric acid in the body is reduced uric acid excretion by kidneys which is genetically determined So from all this you can understand the only thing in your hand is diet control but this is not a major contributing factor of the problem So reduce the intake of purine rich foods such as sea foods, red meat and fructose rich foods such as processed bakery items and soft drinks should be limited and alcohol especially beer should be avoided and reduction of weight is also suggested by regular exercise and increase the intake of vitamin c rich foods such as citrus fruits Disclaimer don't except any drastic change in improvement after dietary changes as uric acid is already deposited in your joints Now coming to the most important part the pharmacological treatment During gout episode we usually give colchicine 0.5mg twice or thrice daily ,oral NSAIDS like indomethacin can also be given but we prefer colchicine here The drug you are taking is allopurinol which increases the excretion of uric acid in the urine should not be given during the period of the gout flare but after the episode subsides to prevent the recurrence so should not be given during initial episode , we start with initial dose of 100mg daily Allopurinol initially causes dissolution of uric acid crystals already deposited so it temporarily causes increase of uric acid levels in the body so initially after start of treatment of allopurinol you get more flareups of gout but gradually the uric acid levels will stabilise and episodes will reduce so stay strong and also the initial dose in your case is 300mg which is high in my view so your fluctuations of uric acid is more than expected so more gout flare, so be patient it will work The dose of allopurinol can be increased by 100mg every 4 weeks until the uric acid levels in the body stabilises After all this if there is no sufficient improvement then there is febuxostat which can replace allopurinol Don't stress too much on dietary changes , but try as much possible, highly restrictive diet not necessary Hope this helps, I know it's difficult now but stay strong the condition will improve but remember this is long term battle @pichhipullayya how is the explanation, satisfied 😂 100% right take take allopurinol for life once you’re set with pain. I tried all diets, no alcohol for 2 years nothing worked for me. I had that feeling why should i take a medicine for lifelong i’ll just change my habits. In process of losing weight i got attacks again, i gave up and started meditation and no attacks from 1 year. Also allopurinol will dissolve existing crystals in joints which cannot be done by diet change. If you want to try diet. Do a strict diet for 3 months and get tested again for uric acid and if value is not normal don’t waste your time. More the time you waste more crystals might form in joints. Sometimes you have to agree that side affects caused by meditation is less harmful than what the decease/condition will cost you in the long term without meditation. Don’t worry just bear the pain for few days and start allopurinol. I also tried homeopathy, cherry extract tablets, what not, nothing worked except allopurinol 3 Quote
psycopk Posted January 23 Report Posted January 23 26 minutes ago, pichhipullayya said: @psycopk please do the needful. Evaru aaina search chesinapudu vatsadi le… cant pin kada Quote
gothamprince Posted January 23 Report Posted January 23 19 minutes ago, jefferson1 said: thank you i am taking one allo 100mg tablet every day its around 5 now. can i bring it down more as it is a good idea? going through same problem as you Around 5 is good if you don't have flare ups , it's varies with each individual but what's important is whether you are having flares with that level No It is not advisable to reduce uric acid levels too much as uric acid has antioxidant effect which is protective to the neurons Very low level of uric acid is shown to increase the risk of dementia, Parkinson's, multiple sclerosis etc Quote
gothamprince Posted January 23 Report Posted January 23 9 minutes ago, Express_Raja said: 100% right take take allopurinol for life once you’re set with pain. I tried all diets, no alcohol for 2 years nothing worked for me. I had that feeling why should i take a medicine for lifelong i’ll just change my habits. In process of losing weight i got attacks again, i gave up and started meditation and no attacks from 1 year. Also allopurinol will dissolve existing crystals in joints which cannot be done by diet change. If you want to try diet. Do a strict diet for 3 months and get tested again for uric acid and if value is not normal don’t waste your time. More the time you waste more crystals might form in joints. Sometimes you have to agree that side affects caused by meditation is less harmful than what the decease/condition will cost you in the long term without meditation. Don’t worry just bear the pain for few days and start allopurinol. I also tried homeopathy, cherry extract tablets, what not, nothing worked except allopurinol Good for you, trust the process Quote
Recommended Posts
Join the conversation
You can post now and register later. If you have an account, sign in now to post with your account.