Ayurveda's logic to have male or female kid

[Spartan]

On 8/16/2025 at 2:15 AM, rational said:

 

Simplified version lo cheppa

Sperm cell carries 23 chromosomes ( 22 autosomes+ one X) or (22 autosomes +one Y). Once either the sperm X or sperm Y chromosome cell penetrates the egg, the egg goes through cortical reaction which hardens the the outer shell of the egg and wont allow any other sperm. Only one sperm is allowed. If Y enters its a boy and X enters its a girl. There is no chance of both entering an egg. The difference between the X and Y is very tiny, if a medication is used chances are it effects both the chromosomes. 

 

ani nuvvu anukuntunnav....but manaki teliyani science vallaki telisi undochu kada....  

[rational]

22 minutes ago, Sinthakai said:

I didn't say it sir. I was actually following your lead here. Need to question the legitimacy of the books.

You need to the read the post clearly, a books lo unna daaniki corraborative gaa physical evidence aa videos kooda vesaanu. If you have read you could have understood. 

[Sinthakai]

29 minutes ago, rational said:

You need to the read the post clearly, a books lo unna daaniki corraborative gaa physical evidence aa videos kooda vesaanu. If you have read you could have understood. 

I did, infact, go through the posts buddy. I couldn't find anything solid in there. You seem to think whatever was said against your argument alone needs to be logical.

[rational]

On 8/18/2025 at 8:38 PM, Spartan said:

ani nuvvu anukuntunnav....but manaki teliyani science vallaki telisi undochu kada....  

Nannu anukuntunnavu antunnavu, mari “manaki teliyani science vallaki telisi undochu kada.... “idhi anukovatam kadha? Anukovadaani emundhi ennaina anukovachu Can we explain it with reason is important. This is my explanation why it doesn’t work like that.

Sperm cell

Sperm cell consists of three parts:

Head - containing the nucleus with genetic material acrosome for egg penetration;

Midpiece- packed with mitochondria which provides the energy for mobility

Tail - that propels the sperm toward the egg.

https://pubmed.ncbi.nlm.nih.gov/30576284/

https://pubmed.ncbi.nlm.nih.gov/31416446/

 

Difference between a Sperm with X chromosome and Y chromosome

Head of a Sperm cell size: Human sperm cells X or Y have a specific range

The head of a typical human sperm cell is approximately 4.5 to 5.5 micrometres (μm) in length and 2.5 to 3.5 μm in width. The size difference between an X and Y sperm is estimated to be only about 0.2 to 0.6 micrometres in total area or volume. This difference is less than 1%. The only confirmed and reliable physical difference is the genetic content and the subsequent ~2.8% difference in DNA amount. This the only difference in the head

Based on the sperm production some X sperm cells could be smaller than Y cells and vice versa. Identifying the difference between X and Y based on head size is not possible.

So, the medicine can’t identify the difference, to attack X chromosome or Y chromosome based on the head size

Mid piece

This where the energy is produced for the sperm cell. The size varies depending on the individual sperm cell not because if it is an x or y sperm cell. This variation is related to the health, maturity, and function of the individual sperm cell. It is not a reliable or consistent indicator of whether the sperm carries an X or a Y chromosome.

The medicine can’t distinguish between X or Y chromosome sperm cell based on the mitochondria size.

The Tail

Functioning as a unified propulsion unit, the tail harnesses energy from its mitochondrial-packed midpiece, translates it into movement via the axoneme motor, and is stabilized by a fibrous sheath—all synergistically driving the sperm forward. All the sperms have the same structure, working method depending on how matured or healthy your sperm cell is.

This shows that orally taken medicine can’t be prepared based on the shape and size of sperm tail to target it.

[rational]

Basic Human Body mechanism for a medicine

Any oral medicine taken be it ayurveda, allopathy, homeopathy goes into the stomach and gets disintegrated and dissolved. Then passes through the small intestine and absorbed into the blood stream and enters liver.  The medicine that survives the first pass metabolism will be pumped out of liver into the blood stream which circulates into the whole body. The blood stream carries the medicine to the cells in your muscles, brain, lungs, etc in a body.

Every cell contains Receptors when a drug attaches to these receptors the drug starts working to get the desired result like destroy the protein, stop it from multiplying, therapeutic effect etc, this is called the lock and key effect. (I am using lame terms to simplify it but a lot goes in this process if you are interested you can read about it there is tons of literature, also study about how difficult it is to design a targeted medicine or ask a pharmacist, geneticist or a doctor)

Similarly, the sperm cells also have receptors to absorb a specific medicine. X and Y chromosomes have identical receptors because both X and Y sperm are produced by the same man, they share 99.9% of their genetic code. The genes responsible for building the sperm's structure, including the proteins and receptors on its surface, are identical in both types and their main goal is to find an egg so u won’t find any difference in the physical properties. The only difference is the genetic code carried by them. There is list of receptors CATSPER, ZP3 etc (you can find the information online)

I will give some examples of receptors in a sperm cell which are unique to them and also common in other cells

Unique receptors

1)     CATSPER channel – calcium influx for hyperkinetic movement.

Found Only in Sperm Cell, but in both X and Y sperms

2)     IZUMO1 receptor -- Fusion with the egg membrane. Binds to JUNO on the egg.

Found in both X and Y sperm cells as it helps in fusion with Egg membrane.

If a so-called Sage’s science medication that binds to these receptors it can affect both X and Y in the same manner as both have these receptors.

Common Receptors

These are found in other cells of the human body too. Some examples

1)     Cannabinoid Receptors

Found in sperm and Skin & Epithelial Tissues: Cell growth and division

2)     Progesterone – which triggers calcium influx and acrosome reaction.

Found in sperm cell and also in Central Nerve System.

Thes are some examples and there are many other receptors which are available in a Sperm cell are also found on Skin, brain, muscle, immune cells, retina etc.

So, if a medicine taken orally can also lock with one of these receptors in your entire body as the medication enters your blood stream.

In Conclusion if a medicine taken orally passes through women’s blood stream not effecting other parts of the body and somehow reaches the female reproductive system and waits for the target (sperm cells) and specifically attacks X chromosome sperms even though both X and Y have similar physical properties and receptors is highly unlikely.

Dosage which is the core aspect of any medicine, which is not mentioned.

For some miracle reason let’s consider the scenario where the medicine identifies the sperm cell depending on the DNA of X chromosome and damages the DNA (as X and Y have different DNA where difference is less than 1%). Since this medicine is taken orally it damages the whole body because every part of your body has X chromosomes.

[rational]

In simple analogy

If X car (sperm) and Y car (sperm) are of same model manufactured from the same company (male reproductive system). X car carrying extra tire (Extra DNA) and Y car carrying no tire (Less DNA) rest of the parts are same as they are of same model.  If they are racing on same track (female reproductive system) and travelling through the pool of fire(medicine), chances are both the cars (X and Y sperm) will catch fire(effected).

If my entire explanation is not satisfactory, try to contact a doctor, pharmacist or a geneticist, they can better explain why it is not possible with orally taken medicine.

[american_desi]

 

@rational Here's what Muslims believe. Your opinion on this ?

 

Hadith about a Child’s Gender

 

Imam Ahmad recorded that Ibn `Abbas said, “A group of Jews came to Allah’s Prophet and said, `Talk to us about some things we will ask you and which only a Prophet would know.’ He said, `Ask me about whatever you wish. However, give your pledge to Allah, similar to the pledge that Ya`qub took from his children, that if I tell you something and you recognize its truth, you will follow me in Islam.’ They said, `Agreed.’ The Prophet said, `Ask me about whatever you wish.’ They said, `Tell us about four matters: 1. What kinds of food did Isra’il prohibit for himself 2. What about the sexual discharge of the woman and the man, and what role does each play in producing male or female offspring 3. Tell us about the condition of the unlettered Prophet during sleep, 4. And who is his Wali (supporter) among the angels’ The Prophet took their covenant that they will follow him if he answers these questions, and they agreed. He said, `I ask you by He Who sent down the Tawrah to Musa, do you not know that Isra’il once became very ill When his illness was prolonged, he vowed to Allah that if He cures His illness, he would prohibit the best types of drink and food for himself. Was not the best food to him camel meat and the best drink camel milk’ They said, `Yes, by Allah.’ The Messenger said, `O Allah, be Witness against them.’ The Prophet then said, `I ask you by Allah, other than Whom there is no deity (worthy of worship), Who sent down the Tawrah to Musa, do you not know that man’s discharge is thick and white and woman’s is yellow and thin If any of these fluids becomes dominant, the offspring will take its sex and resemblance by Allah’s leave. Hence, if the man’s is more than the woman’s, the child will be male, by Allah’s leave. If the woman’s discharge is more than the man’s, then the child will be female, by Allah’s leave.’ They said, `Yes.’ He said, `O Allah, be Witness against them.’ He then said, `I ask you by He Who sent down the Tawrah to Musa, do you not know that the eyes of this unlettered Prophet sleep, but his heart does not sleep’ They said, `Yes, by Allah!’ He said, `O Allah, be Witness.’ They said, `Tell us now about your Wali among the angels, for this is when we either follow or shun you.’ He said, `My Wali (who brings down the revelation from Allah) is Jibril, and Allah never sent a Prophet, but Jibril is his Wali.’ They said, `We then shun you. Had you a Wali other than Jibril, we would have followed you.’ On that, Allah, the Exalted revealed,

[rational]

12 hours ago, american_desi said:

 

@rational Here's what Muslims believe. Your opinion on this ?

 

Hadith about a Child’s Gender

 

2. What about the sexual discharge of the woman and the man, and what role does each play in producing male or female offspring

 `I ask you by Allah, other than Whom there is no deity (worthy of worship), Who sent down the Tawrah to Musa, do you not know that man’s discharge is thick and white and woman’s is yellow and thin If any of these fluids becomes dominant, the offspring will take its sex and resemblance by Allah’s leave. Hence, if the man’s is more than the woman’s, the child will be male, by Allah’s leave. If the woman’s discharge is more than the man’s, then the child will be female, by Allah’s leave.’ 

who ever thinks that this is how the child sex is determined is an idiot. they cant provide any scientific evidence supporting it.  And who ever thinks this is science has zero knowledge how procreation works.  The problem is that like i mentioned before that govt is promoting ayurveda and allopathy under Aayush ministry, which doesnt have proper scientific approach. This unscientific medicines became a million dollar industry.

They cant determine till now how " vaatha, pitha, kapah" are identified and what is their relation or how it can be measured. 

some examples of liver damages caused by ayurveda

Turmeric

 

Figure 3.

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Turmeric-induced spur cell anemia in a patient with compensated cirrhosis. The retrieved turmeric powder supplement is shown in A; B and C (Wright Giemsa stain, 40 ×) shows the presence of spur cells and resolution of spur cells on turmeric withdrawal. On rechallenge (D and E; Wright-Giemsa stain, 40 ×) with turmeric supplement, spur cells reappeared without the need for blood transfusion, only to resolve after withdrawing the offending agent again.

Commiphora wightii or mukul and Boswellia serrata (Guggul, Guggulu or Gugulipid)

Guggul is the gum resin procured from the white sap of various plants used in Ayurvedic practice

Figure 4.

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Guggul-related liver toxicity. The liver histopathology showed zone 3 necrosis extending to the portal region [A, hematoxylin and eosin (H&E) stain, 40 ×] with mixed neutrophilic and eosinophilic inflammation of the portal region associated with severe ductular reaction and early fibrosis (B, H&E stain, 100 ×). Associated moderate to severe canalicular cholestasis is also noted (C, H&E stain, 40 ×).

Cassia angustifolio (Indian Senna)

Cassia angustifolio (Indian Senna)

 The authors concluded that ”poor metabolizers” of phase I hepatic detoxification were predisposed to severe liver injury due to senna[43]. Vanderperren et al[44] demonstrated that chronic ingestion of large amounts of senna fruits in the form of herbal tea led to ALF associated with acute kidney injury and severe coagulation failure in a 52-year old woman. Investigations revealed large amounts of cadmium on urine toxicology consistent with possible contamination of the herbal product with heavy metals[44]. Cadmium is a well-known cumulative nephrotoxic and hepatotoxic agent, demonstrated in multiple Ayurvedic herbal products as a contaminant or adulterant and associated with severe liver injury[4,5,45,46]. Severe hepatotoxicity leading to fatal ALF was noted in an older woman consuming Senna occidentalis (S. occidentalis) herb for constipation. S. occidentalis is a common weed that is considered highly toxic to cattle and small herbivores. Recurrent annual outbreaks of a hepato-myo-encephalopathy syndrome in children in western Uttar Pradesh in India due to S. occidentalis poisoning was also reported by Vashishtha et al[47,48]. In the absence of proper regulatory standards, oversight, and poor manufacturing practices associated with Ayurvedic medicines, contamination of classical senna preparations with similar but more toxic herbs remain a possibility for causes concerning sporadic liver injuries[49]. Portal vein thrombosis due to consumption of boiled, dried Indian senna leaves in a 42-year old woman without underlying comorbid disease or prothrombotic conditions was also reported in the literature[50]. To summarize, senna is associated with severe hepatocellular and cholestatic liver injury and possible renal injury due to the presence of anthraquinone alkaloids in predisposed patients. The clinical course is usually self-limiting with liver toxicity proven on re-challenge; however, in rare instances, fatal ALF has been reported.

Aloe barbadensis mille (aloe vera)

(taken orally)

Figure 5.

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Aloe vera-induced liver injury in a middle-aged diabetic woman. The percutaneous liver histopathology showed porto-portal bridging necrosis [A, hematoxylin and eosin (H&E) stain, 200 ×] associated with moderate to severe ballooning of hepatocytes, hepatocyte fall out and neutrophilic satellitosis (B, H&E stain, 400 ×). Severe intrahepatic and canalicular cholestasis is also noted (C, H&E stain, 400 ×).

Morinda citrifolia (Indian mulberry or Noni juice)

Current literature on the hepatotoxicity of noni juice demonstrates a possible self-limiting idiosyncratic type of herb-induced liver injury, probably due to anthraquinones, presenting with a severe hepatocellular type of liver damage with a predominance of eosinophilic portal inflammation, central necrosis, and cholestasis.

Ayurvedic herbs containing pyrrolizidine alkaloids

 

 

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Hepatic sinusoidal obstruction syndrome in a young male who consumed Holarrhena antidysenterica, known to contain pyrrolizidine alkaloids. Transjugular liver biopsy was performed in view of ascites. The liver histology showed fairly preserved portal areas with extensive sinusoidal dilatation in all zones associated with early sinusoidal and peri-sinusoidal fibrosis [A and B, hematoxylin and eosin (H&E) stain, 400 ×]; the sinusoidal fibrosis is quite evident on Masson-trichrome stain (C, 400 ×); after one year follow-up, in view of recurrence of ascites and acute variceal bleeding, a repeat liver biopsy was performed which revealed prominent sinusoidal dilatation with sinusoidal and portal fibrosis (D, H&E stain, 200 ×) and cirrhosis changes with bridging fibrosis and partial nodule formation (E, Masson-trichrome stain, 200 ×). The retrieved over-the-counter herbal supplement is shown (F).

https://pmc.ncbi.nlm.nih.gov/articles/PMC7522561/

https://pmc.ncbi.nlm.nih.gov/articles/PMC6040517/pdf/bcr-2018-225590.pdf

 

[rational]

Fig. 2. Ayurvedic medication prescribed by a registered practitioner for a patient with vague digestive complaints.

Open in a new tab

Multiple medicines (A) were taken over a period of 1 month, leading to severe bilateral leg edema and ascites; transjugular liver biopsy revealed features of extensive lymphocytic and eosinophilic infiltration of sinusoids associated with sinusoidal dilatation (B, hematoxylin and eosin stain, 40×); giant cell transformation of hepatocytes (C, H&E stain, 400×); multiple scattered granulomas in the lobular and portal areas (D and E, H&E stain, 400×) suggestive of granulomatous hepatitis with sinusoidal obstruction. Taken together, the Ayurvedic medications had close to 50 different types of herbal and nonherbal components.

Abbreviation: H&E, hematoxylin and eosin.

https://pmc.ncbi.nlm.nih.gov/articles/PMC5497007/

[krishnaaa]

On 8/14/2025 at 3:18 AM, rational said:

Sushruta Samhita, volume 3: Sharirasthana

Chapter III - Pregnancy

Period of Menstruation:—
The process (menstruation) commences at the twelfth year, flowing once in every month, and continues till the fiftieth[1] year when it disappears with the sensible decay of the body. 8

A visit[3] to one’s wife on even days during the catamenial period (twelve days in all from the cessation of the flow) leads to the conception of a male child while an intercourse on odd days results in the birth of a daughter. Hence a man, seeking a male-issue, should approach his wife for the purpose in a clean body and with a quiet and calm spirit on an even date. 9.

A sense of fatigue and physical languor, thirst, lassitude and weariness in the thighs, suppression of the flow of semen and menstrual secretion (Sukra and Sonita) out of the uterus (Yoni), and throbbing in the organ (after coition) are symptoms of a recent fecundation. 10.

Memorable verses:—
Those women who are devout in their worship of the gods and the Brahmins and cherish a clean soul in a clean body during pregnancy are sure to be blest with good, virtuous and generous children; whereas a contrary conduct during the period is sure to be attended with contrary fruits. The development of the limbs and the members etc. of a fetus in the womb is natural and spontaneous, and the qualities and conditions which mark these organs are determined by the acts of the child which are anterior to its genesis and were done in its prior existence. 21–22.

https://www.wisdomlib.org/hinduism/book/sushruta-samhita-volume-3-sharirasthana/d/doc142881.html

Here is my theory after observing many couples.

Sex of the child depends on which parent is more in need of support.

Mothers under stress or greater yearning for an offspring would have a greater chance of boy. You can see many families where father is carefree but mothers facing financial or societal struggles usually conceive boys.

If the father is under more stress comparatively or has greater yearning to have kids, there is a greater chance of a girl child who would lend emotional support. This is the reason as to why top fighters in the army mostly have girl children.

If both parents are around an equal level then its 50:50

[jpismahatma]

4 hours ago, krishnaaa said:

Here is my theory after observing many couples.

Sex of the child depends on which parent is more in need of support.

Mothers under stress or greater yearning for an offspring would have a greater chance of boy. You can see many families where father is carefree but mothers facing financial or societal struggles usually conceive boys.

If the father is under more stress comparatively or has greater yearning to have kids, there is a greater chance of a girl child who would lend emotional support. This is the reason as to why top fighters in the army mostly have girl children.

If both parents are around an equal level then its 50:50

Life ni baga chadivinavu anna.

[rational]

5 minutes ago, krishnaaa said:

Here is my theory after observing many couples.

Sex of the child depends on which parent is more in need of support.

Mothers under stress or greater yearning for an offspring would have a greater chance of boy. You can see many families where father is carefree but mothers facing financial or societal struggles usually conceive boys.

If the father is under more stress comparatively or has greater yearning to have kids, there is a greater chance of a girl child who would lend emotional support. This is the reason as to why top fighters in the army mostly have girl children.

If both parents are around an equal level then its 50:50

if you studied the scientific research i posted you will get an idea on how procreation works. 

For instance, your left and right lung have the same essential job: to inhale oxygen. While one is slightly smaller to make room for the heart, this size difference doesn't change their core function. if you are under stress they both try to inhale oxygen.

In the same way, both X and Y sperm share a single, vital mission: to race towards and fertilize the egg. They are both built for this identical journey. The only significant difference between them is the single chromosome they carry, a small genetic package that ultimately determines the biological sex of the child. Genetic instruction is the only difference.

"If a female is under significant stress, it can disrupt her ovulation, potentially preventing the release of an egg. Even if an egg is released, stress can alter the reproductive environment in ways that might affect sperm. However, since X and Y sperm are so physically similar, this stress does not favor one type over the other significantly.

"If a male is under chronic stress, the body's primary response is a reduction in overall sperm production and quality. However, the process that determines chromosome type continues, meaning both X and Y sperm are still generated.

In one ejaculation around 80 million to 300 million sperm cells is released (this is not a small number) and they swim through the female reproductive system to reach the egg and female immune system kills the sperm cells identifying it as a foreign body, only a few sperms reaches an egg and try to penetrate so its an ugly race. 

If you see the video you can observe how randomly the sperm cells move and attach to an egg. you can see that all the x and y sperms look alike and functioning similarly. (just slow it down for better observation). 

stress can decrease the chances of producing an egg or delay in a female but not in choosing x or y sperm to attach to its egg. Stress can decrease the sperm count but highly unlikely that it can decide the gender of the baby,

Because there are lot of factors that effect the procreation, like age, timing, frequency, previous pregnancy, life style, medical conditions, weight, stress etc. internal factors in the female uterus like, PH, uterine contraction, sperm reservoir, immune system etc. All these factors play a role in procreation.

Personal observation is not considered as evidence because, it's only one person's story and ignoring all others factors in procreation and relying only on stress as reason for the gender is not fair assumption. if you can do RCT (randomize control trial) and double blind test then that adds more evidence to your theory. it is highly unlikely that your theory is right because we can be sure from the science research that stress plays a role in overall having a baby but not selecting the gender a baby because there other major influential factors too which are ignored in you theory.

Selecting the gender of a baby can only done using IVF (in vitro fertilization, but to select an X sperm or Y sperm a certain type of dye (Hoechst 33342) is applied to reveal the  DNA structure of the sperm. by selecting this dyed sperm we can fertilized an egg with favorable gender. Doing it in humans is unethical. i think they used it animal.

https://www.sciencedirect.com/science/article/abs/pii/S0093691X0800664X

how IVF is done

[krishnaaa]

2 hours ago, rational said:

if you studied the scientific research i posted you will get an idea on how procreation works. 

For instance, your left and right lung have the same essential job: to inhale oxygen. While one is slightly smaller to make room for the heart, this size difference doesn't change their core function. if you are under stress they both try to inhale oxygen.

In the same way, both X and Y sperm share a single, vital mission: to race towards and fertilize the egg. They are both built for this identical journey. The only significant difference between them is the single chromosome they carry, a small genetic package that ultimately determines the biological sex of the child. Genetic instruction is the only difference.

"If a female is under significant stress, it can disrupt her ovulation, potentially preventing the release of an egg. Even if an egg is released, stress can alter the reproductive environment in ways that might affect sperm. However, since X and Y sperm are so physically similar, this stress does not favor one type over the other significantly.

"If a male is under chronic stress, the body's primary response is a reduction in overall sperm production and quality. However, the process that determines chromosome type continues, meaning both X and Y sperm are still generated.

In one ejaculation around 80 million to 300 million sperm cells is released (this is not a small number) and they swim through the female reproductive system to reach the egg and female immune system kills the sperm cells identifying it as a foreign body, only a few sperms reaches an egg and try to penetrate so its an ugly race. 

If you see the video you can observe how randomly the sperm cells move and attach to an egg. you can see that all the x and y sperms look alike and functioning similarly. (just slow it down for better observation). 

stress can decrease the chances of producing an egg or delay in a female but not in choosing x or y sperm to attach to its egg. Stress can decrease the sperm count but highly unlikely that it can decide the gender of the baby,

Because there are lot of factors that effect the procreation, like age, timing, frequency, previous pregnancy, life style, medical conditions, weight, stress etc. internal factors in the female uterus like, PH, uterine contraction, sperm reservoir, immune system etc. All these factors play a role in procreation.

Personal observation is not considered as evidence because, it's only one person's story and ignoring all others factors in procreation and relying only on stress as reason for the gender is not fair assumption. if you can do RCT (randomize control trial) and double blind test then that adds more evidence to your theory. it is highly unlikely that your theory is right because we can be sure from the science research that stress plays a role in overall having a baby but not selecting the gender a baby because there other major influential factors too which are ignored in you theory.

Selecting the gender of a baby can only done using IVF (in vitro fertilization, but to select an X sperm or Y sperm a certain type of dye (Hoechst 33342) is applied to reveal the  DNA structure of the sperm. by selecting this dyed sperm we can fertilized an egg with favorable gender. Doing it in humans is unethical. i think they used it animal.

https://www.sciencedirect.com/science/article/abs/pii/S0093691X0800664X

how IVF is done

Asked chatgpt

 

Yes, stress in fathers is associated with a higher likelihood of fathering daughters, while some research suggests a higher likelihood of fathering sons when the father has anxiety disorders. This effect is sex-specific and potentially linked to changes in the father's sperm quality, such as microRNA content, which can alter gene expression in the offspring and influence their development and stress response. 

Evidence for Stressed Dads and Daughters

Sex-Specific Effects: Research indicates a sex-specific effect of paternal stress, with chronic stress on male rodents leading to an increase in the birth of female offspring. 

Sperm Quality: Studies show that stress in fathers can alter microRNA in their sperm. These microRNA are vesicles that can fuse with the egg, potentially affecting the genes of the offspring. 

Evidence for Stressed Dads and Sons 

Anxiety Disorders: A different study found a positive association between a father's lifetime history of physician-diagnosed anxiety disorders and an increased likelihood of having a male infant. This suggests that paternal stress may, in some cases, be linked to an excess of male births.

Mechanisms and Epigenetic Link

Epigenetic Changes: The changes in microRNA are a form of epigenetic alteration, meaning they don't change the DNA sequence but influence how genes are expressed. 

Offspring Development: Paternal stress, via these sperm changes, can affect the offspring's brain development and their response to stress. This includes changes in DNA methylation and the development of the hypothalamus, which plays a role in stress response. 

Important Considerations

Complexity: The relationship between paternal stress and offspring sex is complex, with different types of stress and different populations showing varied outcomes. 

Further Research: More research is needed in humans to fully understand the timing of germ cell vulnerability to these stressors. 

[rational]

1 hour ago, krishnaaa said:

Asked chatgpt

 

Yes, stress in fathers is associated with a higher likelihood of fathering daughters, while some research suggests a higher likelihood of fathering sons when the father has anxiety disorders. This effect is sex-specific and potentially linked to changes in the father's sperm quality, such as microRNA content, which can alter gene expression in the offspring and influence their development and stress response. 

Evidence for Stressed Dads and Daughters

Sex-Specific Effects: Research indicates a sex-specific effect of paternal stress, with chronic stress on male rodents leading to an increase in the birth of female offspring. 

Sperm Quality: Studies show that stress in fathers can alter microRNA in their sperm. These microRNA are vesicles that can fuse with the egg, potentially affecting the genes of the offspring. 

Evidence for Stressed Dads and Sons 

Anxiety Disorders: A different study found a positive association between a father's lifetime history of physician-diagnosed anxiety disorders and an increased likelihood of having a male infant. This suggests that paternal stress may, in some cases, be linked to an excess of male births.

Mechanisms and Epigenetic Link

Epigenetic Changes: The changes in microRNA are a form of epigenetic alteration, meaning they don't change the DNA sequence but influence how genes are expressed. 

Offspring Development: Paternal stress, via these sperm changes, can affect the offspring's brain development and their response to stress. This includes changes in DNA methylation and the development of the hypothalamus, which plays a role in stress response. 

Important Considerations

Complexity: The relationship between paternal stress and offspring sex is complex, with different types of stress and different populations showing varied outcomes. 

Further Research: More research is needed in humans to fully understand the timing of germ cell vulnerability to these stressors. 

Dont stop your question there because this research focuses on stress but  other factors like ages, diet, lifestyle, etc are controlled which will effect the outcome. in real life scenario these factors vary and cannot be controlled.

ask chatgpt the next question. 

"In real life scenario of male and female procreation how accurate is the research on stress to determine the outcome of the gender"

Post it here lets see what the ChatGPT says

eventually that's what you observed in real life right? "stress in father female off spring and stress in mother male of spring"

[krishnaaa]

19 minutes ago, rational said:

Dont stop your question there because this research focuses on stress but  other factors like ages, diet, lifestyle, etc are controlled which will effect the outcome. in real life scenario these factors vary and cannot be controlled.

ask chatgpt the next question. 

"In real life scenario of male and female procreation how accurate is the research on stress to determine the outcome of the gender"

Post it here lets see what the ChatGPT says

eventually that's what you observed in real life right? "stress in father female off spring and stress in mother male of spring"

Just did....looks like science hasnt caught up yet.