Arranged Marriage on Jimmy Kimmel show

[YeddiBK]

15 minutes ago, RunRaajaRun123 said:

Arranged marriage is shitty concept, there is nothing wrong in making fun of it.

[kittaya]

55 minutes ago, Biskot said:

thana ke oka 40 untey... me age antha uncle...

Uncle girism ... Barrister parvathisam story rasinappudu 10th charuvutha untadu aemo Ani doubt

[RunRaajaRun123]

14 minutes ago, YeddiBK said:

Ofcourse it is one of the oldest traditions followed in India.

With arranged marriages a diversfied gene pool is not being created.

when people marry into same castes as most of them have  similar genes making the bad genes pass through generations.

 

[Ara_Tenkai]

31 minutes ago, RunRaajaRun123 said:

Arranged marriage is shitty concept, there is nothing wrong in making fun of it.

haha pelli ayyinda brotheru... inka bachelor vena....

[Ara_Tenkai]

2 minutes ago, RunRaajaRun123 said:

Ofcourse it is one of the oldest traditions followed in India.

With arranged marriages a diversfied gene pool is not being created.

when people marry into same castes as most of them have  similar genes making the bad genes pass through generations.

 

true... marrying in a same caste is not good but in general arranged marriage is not bad... i cannot explain it here as the arranged marriage concept has found a new definition these days with help of online matrimony sites..

[kalajamoon]

3 minutes ago, RunRaajaRun123 said:

Ofcourse it is one of the oldest traditions followed in India.

With arranged marriages a diversfied gene pool is not being created.

when people marry into same castes as most of them have  similar genes making the bad genes pass through generations.

 

baa cheppav ba, shitty concept

http://www.thehindu.com/news/cities/Hyderabad/south-asians-prone-to-genetic-diseases-ccmb-study/article19303968.ece

 

South Asians prone to genetic diseases: CCMB study

[kalajamoon]

Just now, Ara_Tenkai said:

true... marrying in a same caste is not good but in general arranged marriage is not bad... i cannot explain it here as the arranged marriage concept has found a new definition these days with help of online matrimony sites..

naa bonda le, inka ave same caste gola, bava maradal sambandhalu last ki movies lo kooda medhavi ani cheppukune 3vikram lanti yedavalu ave soopithandaru. 

 

[kalajamoon]

South Asians prone to genetic diseases: CCMB study

It analysed samples from more than 2,800 individuals from 275 distinct South Asian groups

Every person carries several genetic mutations which if occurred in two copies leads to serious recessive diseases. But, the 1.5 billion people of South Asia were more vulnerable to rare genetic population specific diseases than elsewhere in the world because of the endogamous marriages or marrying with the same ethnicity, community, caste, etc.

A new study led by co-senior authors Kumarasamy Thangaraj of CSIR-Centre for Cellular and Molecular Biology (CCMB) and David Reich of Broad Institute MIT & Harvard, Cambridge, USA, in collaboration with other institutes, has identified that about a third of populations here have had such strong defective genes passed on through generations. “We have analysed samples from more than 2,800 individuals from over 275 distinct South Asian populations belonging to various social and linguistic groups from India, Pakistan, Nepal, Sri Lanka, and Bangladesh using about 600,000 genome-wide markers”, said Mr. Thangaraj flanked by CCMB Director R.K. Mishra at a press conference on Tuesday.

It was found that 81 out of 263 unique South Asian groups, including 14 groups with estimated census sizes of over a million, have a genetic mutation base with recessive diseases much more than the one that occurred in both Finns and Ashkenazi Jews in the West. This source of risk for genetic recessive diseases was different from that due to marriages among close relatives (consanguineous marriages), also a major cause of recessive disease here, said the study published in online edition of ‘Nature Genetics,’ on July 17.

The authors highlighted the case of the Vysya community, with a census size of more than three million and endogamous for centuries where the occurrence of a defective gene causing ailments was about 1.2-fold stronger than in the Finnish population. Vysyas have an approximately 100-fold higher rate of ‘butyrylcholinesterase’ deficiency than other groups, and is a known counter-indication for the use of muscle relaxants such as ‘succinylcholine’ or ‘mivacurium’ given prior to surgery.

The authors had analysed six patients from Hyderabad and Bangalore with a progressive ‘Pseudorheumatoid Dysplasia’ (PPD), a disease known to be caused by mutations. Five were from non-consanguineous marriages and they passed on the genetic mutation to their offspring who died within 10 years as “none could identify the genetic reasons or diagnose the ailments”.

“Our study is an opportunity for discovering population-specific disease causing genes in communities known to pass on such recessive diseases. Mapping mutations of these would help in developing strategies for diagnosis, modifying clinical course and reduce disease burden,” explained Mr. Thangaraj.

Hoping the study would lead to actionable medical research, he cited the example of ‘Dor Yeshorim’, a community genetic testing program among Orthodox Ashkenazi Jews which screens students for common recessive disease causing mutations, creates a confidential database for prospective couples to check and this has helped reduce rate of many recessive diseases to near-zero so a similar strategy could be effective here too. CCMB Director Mr. Mishra said the study will be enable a paradigm shift towards facilitating and accelerating predictive and personalized medicine.

[kalajamoon]

Just now, kalajamoon said:

South Asians prone to genetic diseases: CCMB study

It analysed samples from more than 2,800 individuals from 275 distinct South Asian groups

Every person carries several genetic mutations which if occurred in two copies leads to serious recessive diseases. But, the 1.5 billion people of South Asia were more vulnerable to rare genetic population specific diseases than elsewhere in the world because of the endogamous marriages or marrying with the same ethnicity, community, caste, etc.

A new study led by co-senior authors Kumarasamy Thangaraj of CSIR-Centre for Cellular and Molecular Biology (CCMB) and David Reich of Broad Institute MIT & Harvard, Cambridge, USA, in collaboration with other institutes, has identified that about a third of populations here have had such strong defective genes passed on through generations. “We have analysed samples from more than 2,800 individuals from over 275 distinct South Asian populations belonging to various social and linguistic groups from India, Pakistan, Nepal, Sri Lanka, and Bangladesh using about 600,000 genome-wide markers”, said Mr. Thangaraj flanked by CCMB Director R.K. Mishra at a press conference on Tuesday.

It was found that 81 out of 263 unique South Asian groups, including 14 groups with estimated census sizes of over a million, have a genetic mutation base with recessive diseases much more than the one that occurred in both Finns and Ashkenazi Jews in the West. This source of risk for genetic recessive diseases was different from that due to marriages among close relatives (consanguineous marriages), also a major cause of recessive disease here, said the study published in online edition of ‘Nature Genetics,’ on July 17.

The authors highlighted the case of the Vysya community, with a census size of more than three million and endogamous for centuries where the occurrence of a defective gene causing ailments was about 1.2-fold stronger than in the Finnish population. Vysyas have an approximately 100-fold higher rate of ‘butyrylcholinesterase’ deficiency than other groups, and is a known counter-indication for the use of muscle relaxants such as ‘succinylcholine’ or ‘mivacurium’ given prior to surgery.

The authors had analysed six patients from Hyderabad and Bangalore with a progressive ‘Pseudorheumatoid Dysplasia’ (PPD), a disease known to be caused by mutations. Five were from non-consanguineous marriages and they passed on the genetic mutation to their offspring who died within 10 years as “none could identify the genetic reasons or diagnose the ailments”.

“Our study is an opportunity for discovering population-specific disease causing genes in communities known to pass on such recessive diseases. Mapping mutations of these would help in developing strategies for diagnosis, modifying clinical course and reduce disease burden,” explained Mr. Thangaraj.

Hoping the study would lead to actionable medical research, he cited the example of ‘Dor Yeshorim’, a community genetic testing program among Orthodox Ashkenazi Jews which screens students for common recessive disease causing mutations, creates a confidential database for prospective couples to check and this has helped reduce rate of many recessive diseases to near-zero so a similar strategy could be effective here too. CCMB Director Mr. Mishra said the study will be enable a paradigm shift towards facilitating and accelerating predictive and personalized medicine.

komatollunnara eeda, soodandi vayya

[Ara_Tenkai]

1 minute ago, kalajamoon said:

naa bonda le, inka ave same caste gola, bava maradal sambandhalu last ki movies lo kooda medhavi ani cheppukune 3vikram lanti yedavalu ave soopithandaru. 

 

bava maradal concept ayithe yaak anipistadi... peddama kuthuru chelli ayithadi... mama kuthuru mardal ayithadi... but peddama and mama came from the same mother kada... valla pillalni etla chesukuntaru vaya...

[kalajamoon]

Just now, Ara_Tenkai said:

bava maradal concept ayithe yaak anipistadi... peddama kuthuru chelli ayithadi... mama kuthuru mardal ayithadi... but peddama and mama came from the same mother kada... valla pillalni etla chesukuntaru vaya...

ade ga malli aa nikrushtudu 3vikram gadu adedo goppa ga soopithadu pithre gaadu

[Ara_Tenkai]

Just now, kalajamoon said:

ade ga malli aa nikrushtudu 3vikram gadu adedo goppa ga soopithadu pithre gaadu

paga battesav trivikram meeda... enthaina guruji movies bane untayi bro...

[kalajamoon]

Just now, Ara_Tenkai said:

paga battesav trivikram meeda... enthaina guruji movies bane untayi bro...

atharintiki daredi lo bava maradal sambandham highlight chesthadu ga, aadokkade kaadu le andaru anthe anuko. kaani eedu intellectual ani cutting 10guthadu ga anduke hilite chesa adini

[RunRaajaRun123]

2 minutes ago, Ara_Tenkai said:

true... marrying in a same caste is not good but in general arranged marriage is not bad... i cannot explain it here as the arranged marriage concept has found a new definition these days with help of online matrimony sites..

Most arranged marriages are within the same community,that’s what am referring to.

Even though the marriage is arranged between two different communities I object it. This is simple how can you marry a person without being with them and traveling with them or without knowing how the sexual life will be.

People are literally forced into marriage and many don’t object it after marriage as they fear the draconian so called Indian Culture.

[kalajamoon]

Just now, RunRaajaRun123 said:

Most arranged marriages are within the same community,that’s what am referring to.

Even though the marriage is arranged between two different communities I object it. This is simple how can you marry a person without being with them and traveling with them or without knowing how the sexual life will be.

People are literally forced into marriage and many don’t object it after marriage as they fear the draconian so called Indian Culture.

yeah erri fook culture le baa manadi.