First human trial for coronavirus vaccine begins Monday in the US

[tacobell fan]

The first human trial testing a potential vaccine to prevent COVID-19 began Monday, U.S. health officials confirmed.

The National Institutes of Health, an agency within the Department of Health and Human Services, has been fast-tracking work with biotech company Moderna to develop a vaccine using the current strain of the new coronavirus. The trial is taking place at the Kaiser Permanente Washington Health Research Institute in Seattle, Washington, where COVID-19 cases have surged and authorities have banned mass gatherings. The early-stage, or phase 1, trial will test the vaccine on 45 males and non-pregnant females between the ages of 18 and 55, according to trial details on NIH's website.

There are currently no proven therapies for the latest outbreak, which has killed at least 6,513 and sickened nearly 170,000 people worldwide since emerging from the Chinese city of Wuhan less than three months ago.

Hopes to get a vaccine to market are high, but doctors are setting expectations low for how quickly it can happen. Developing, testing and reviewing any potential vaccine is a long, complex and expensive endeavor that could take months or even years, global health experts say. Before researchers can begin human trials, they must have a firm understanding of the pathogen, run safety tests and find enough human volunteers.

Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, told reporters last week a vaccine ready for public use likely won't be ready for another 12 to 18 months.

He said the potential vaccine by Moderna contains genetic material called messenger RNA, or mRNA, that was produced in a lab. The mRNA is a genetic code that tells cells how to make a protein and was found in the outer coat of the new coronavirus, according to researchers at the Kaiser Permanente Washington Health Research Institute.

The mRNA instructs the body's own cellular mechanisms for making proteins to make those that mimic the virus proteins, thereby producing an immune response.

Fauci told reporters last month a vaccine may not solve "problems in the next couple of months but it certainly would be an important tool that we would have." He said it's possible the virus will prove to be seasonal, thus likely to subside in the warmer months like the flu.

In the meantime, some health authorities are using Gilead Sciences' antiviral drug Remdesivir, which was tested as a possible treatment during the Ebola outbreak. CDC director Robert Redfield said at a separate hearing last week that the drug is being used in Washington state.

[bhaigan]

Just now, tacobell fan said:

In the meantime, some health authorities are using Gilead Sciences' antiviral drug Remdesivir, which was tested as a possible treatment during the Ebola outbreak. CDC director Robert Redfield said at a separate hearing last week that the drug is being used in Washington state.

There are side effects with these remdesvir drug

[perugu_vada]

Mrne stock up by 22% this morning andhu k

[perugu_vada]

2 minutes ago, bhaigan said:

There are side effects with these remdesvir drug

@Catabolite

[superhit3]

voka sari Paracetmol or dani equivalent drug try cheste better ...anavasaram ga billions of dollars, weeks of time and millions pranala to chelagatam yenduku. chethi lo vunna vatini try cheste pola. chankalo pilli (Paracetmol) petukoni vooranta searching ...waste of time

[Catabolite]

27 minutes ago, perugu_vada said:

@Catabolite

Elevated liver enzyme levels, can bet it won't get FDA approval. 

[superhit3]

1 minute ago, Catabolite said:

Elevated liver enzyme levels, can bet it won't get FDA approval. 

aap medical field aa bro?

[Catabolite]

5 minutes ago, superhit3 said:

aap medical field aa bro?

S