drug candidates for the vaccination and treatment of COVID-19:

[Subbulu]

Company/research	Drug/vaccine candidate	Development stage
MIGAL	Infectious Bronchitis Virus (IBV) vaccine	Pre-clinical trials
APEIRON Biologics	APN01	Phase I
Tonix Pharmaceuticals	TNX-1800	Initial evaluation
Innovation Pharmaceuticals	Brilacidin	Initial evaluation
Clover Biopharmaceuticals	S-Trimer vaccine	Pre-clinical trials
Vaxart	TBC	Pre-clinical trials
CytoDyn	Leronlimab	Phase II for HIV and fast tracked for COVID-19
Applied DNA Sciences and Takis Biotech	Linear DNA Vaccine	Pre-clinical trials
BIOXYTRAN	BX-25	TBC
Novavax	MERS coronavirus vaccine	Phase I in 2020
Biocryst Pharma	Galidesivir	Advanced animal testing
Takeda	H-IG therapy	TBC
Heat Biologics	gp96 vaccine	Early development
Pfizer and BioNTech	mRNA vaccine, BNT162	Clinical programme development with Fosun in China
Generex	Ii-Key immune system activation	Clinical programme development in China
Vir Biotechnology/Wuxi Vir Biotechnology/Alnylam	MABs binding to virus siRNA candidates	TBC
Janssen Pharmaceuticals	PREZCOBIX® HIV medication (darunavir/cobicistat)	TBC

[karthik25]

Vaccines ekkuvunnayi... cure ki drug kuda important

[superhit3]

TBC ante? 

[Srin]

32 minutes ago, superhit3 said:

TBC ante? 

To Be Checked anukunta guess though 

[jalsa01]

Andharu vaccine Kosam try chestunnaru... but vachina vallaki treatment medicine evaru cheppatam ledenti...

[superhit3]

5 minutes ago, Srin said:

To Be Checked anukunta guess though 

yemo. actually what does each of Development Stage means ani 3-4 words ani vunte bagundedi.

Clinical programme development? ante already trials done and developing the drug? or it is yet to go to animal trials and human trials?

Pre-clinical trials? meaning animal testing in progress? or human trials going on?

Phase I? 

Phase II?

which one of those are closer to completion? pain 4 stages lo which ones indicates fast ga vundi ani? 

@Catabolite yemaina idea vunte please throw some light. TIA

[karthik25]

22 minutes ago, superhit3 said:

yemo. actually what does each of Development Stage means ani 3-4 words ani vunte bagundedi.

Clinical programme development? ante already trials done and developing the drug? or it is yet to go to animal trials and human trials?

Pre-clinical trials? meaning animal testing in progress? or human trials going on?

Phase I? 

Phase II?

which one of those are closer to completion? pain 4 stages lo which ones indicates fast ga vundi ani? 

@Catabolite yemaina idea vunte please throw some light. TIA

Pre-clinical: animal models lo efficacy, toxicity chustaru.

Phase 1: Human trials for safety

Phase 2: Human trials to check proof of concept. Safety also monitored.

Phase 3: Further Human trials... for efficacy.

All 3 phases clear ayite, drug comes into market. Post-marketing data ni kuda track chestaru. That is called Phase 4.

[karthik25]

Just now, karthik25 said:

Pre-clinical: animal models lo efficacy, toxicity chustaru.

Phase 1: Human trials for safety

Phase 2: Human trials to check proof of concept. Safety also monitored.

Phase 3: Further Human trials... for efficacy.

All 3 phases clear ayite, drug comes into market. Post-marketing data ni kuda track chestaru. That is called Phase 4.

Generally, these take years. But ilanti cases lo fast-track chestaru.

[superhit3]

10 minutes ago, karthik25 said:

Pre-clinical: animal models lo efficacy, toxicity chustaru.

Phase 1: Human trials for safety

Phase 2: Human trials to check proof of concept. Safety also monitored.

Phase 3: Further Human trials... for efficacy.

All 3 phases clear ayite, drug comes into market. Post-marketing data ni kuda track chestaru. That is called Phase 4.

Thank you Brother for enlightening us details. 

[Kalam_Youtheman]

5 hours ago, Subbulu said:

Company/research	Drug/vaccine candidate	Development stage
MIGAL	Infectious Bronchitis Virus (IBV) vaccine	Pre-clinical trials
APEIRON Biologics	APN01	Phase I
Tonix Pharmaceuticals	TNX-1800	Initial evaluation
Innovation Pharmaceuticals	Brilacidin	Initial evaluation
Clover Biopharmaceuticals	S-Trimer vaccine	Pre-clinical trials
Vaxart	TBC	Pre-clinical trials
CytoDyn	Leronlimab	Phase II for HIV and fast tracked for COVID-19
Applied DNA Sciences and Takis Biotech	Linear DNA Vaccine	Pre-clinical trials
BIOXYTRAN	BX-25	TBC
Novavax	MERS coronavirus vaccine	Phase I in 2020
Biocryst Pharma	Galidesivir	Advanced animal testing
Takeda	H-IG therapy	TBC
Heat Biologics	gp96 vaccine	Early development
Pfizer and BioNTech	mRNA vaccine, BNT162	Clinical programme development with Fosun in China
Generex	Ii-Key immune system activation	Clinical programme development in China
Vir Biotechnology/Wuxi Vir Biotechnology/Alnylam	MABs binding to virus siRNA candidates	TBC
Janssen Pharmaceuticals	PREZCOBIX® HIV medication (darunavir/cobicistat)	TBC

ninnna trump gaaadi hydroxychln news ki... all pharma companies mooosukoni kuusunnnayee..exisiting frug working kadha ipppud how to make money ani... Dem gaaaalu ki punch

[perugu_vada]

20 minutes ago, Kalam_Youtheman said:

ninnna trump gaaadi hydroxychln news ki... all pharma companies mooosukoni kuusunnnayee..exisiting frug working kadha ipppud how to make money ani... Dem gaaaalu ki punch

Data undha to support it is working ? @Kalam_Youtheman

[karthik25]

26 minutes ago, superhit3 said:

Thank you Brother for enlightening us details. 

Lab ki velli 2 weeks avutondi bhayya.. I can't live without research. ilanti questions ayina answer cheste edo satisfcation untundi..

[Sucker]

1 minute ago, perugu_vada said:

Data undha to support it is working ? @Kalam_Youtheman

Data ledu bokka ledu MBBS thatha ninna cheppadu ga theeskunte theeskondi lekunte ledu. Adi mee choice ani 

[karthik25]

1 minute ago, perugu_vada said:

Data undha to support it is working ? @Kalam_Youtheman

France lo oka clinical trial on 10 people lo andariki 6 days lo cure ayindani oka report undi.. they are confirming it with more/larger trials. Hope its working.

[karthik25]

3 minutes ago, perugu_vada said:

Data undha to support it is working ? @Kalam_Youtheman

 

Just now, karthik25 said:

France lo oka clinical trial on 10 people lo andariki 6 days lo cure ayindani oka report undi.. they are confirming it with more/larger trials. Hope its working.

Hyroxychloroquine + Azithromycin combo was used in the trial. Ippudu market lo veeti koratha undi.. andaru egabadi konestaru...