So depressing today

[Cool]

Enduko thelidu but so depressing that asal work cheyabuddi avvadam ledu.

[Anais_nin]

climate change

season change

takes time to adjust

[PilliBeta]

It's all in your head. 

[Spartan]

today is Dussera Ashtami Pooja at home.

[Anais_nin]

9 minutes ago, PilliBeta said:

It's all in your head. 

In this 3-year study of CSF monoamine turnover (N=479), we confirm that 5-HIAA concentrations fit a cosine model that displays a peak in spring and a trough in fall. We additionally show that a significant proportion of the variance (5.4%) in 5-HIAA concentrations is explained by seasonality. Furthermore, we demonstrate a dose-dependent association of the 5-HTTLPR s-allele with seasonality of 5-HT turnover, whereas this polymorphism was not associated with absolute 5-HIAA levels. Finally, 5-HIAA seasonality correlated positively with depressive symptoms.

[Vallavan]

12 minutes ago, Anais_nin said:

In this 3-year study of CSF monoamine turnover (N=479), we confirm that 5-HIAA concentrations fit a cosine model that displays a peak in spring and a trough in fall. We additionally show that a significant proportion of the variance (5.4%) in 5-HIAA concentrations is explained by seasonality. Furthermore, we demonstrate a dose-dependent association of the 5-HTTLPR s-allele with seasonality of 5-HT turnover, whereas this polymorphism was not associated with absolute 5-HIAA levels. Finally, 5-HIAA seasonality correlated positively with depressive symptoms.

ante enti bro. I just got 5-HTP supplements for mood and sleep.

[NYCpal]

Ee festivals endhuku vasthayi on weekends ..family already preparing special dishes and my diet gone ..thought of going on fast and start fresh from Monday ..ughhh how much I hate this season 

[Anais_nin]

5 minutes ago, Vallavan said:

ante enti bro. I just got 5-HTP supplements for mood and sleep.

serotonin metabolite ni 5-htt/ 5-hiaa antaru...

it regulates mood...its present in cerebrospinal fluid...

when seasons change ..it also changes in volume.....fall lo takkuva untadi serotonin...so more chances of depression

[LadiesTailor]

33 minutes ago, Cool said:

Enduko thelidu but so depressing that asal work cheyabuddi avvadam ledu.

Eat chocolate for better mood 

[Chay]

pakkana edaina casino unte oka 3-4 hours spend sesi ra baa.. refreshing ga untundi

[Manikyam]

7 minutes ago, LadiesTailor said:

Eat chocolate for better mood 

maradal iste aa chweetness verabba

[raaajaaa]

bro pakka idi ade careful ga undu

[Sarvapindi]

1 hour ago, Chay said:

pakkana edaina casino unte oka 3-4 hours spend sesi ra baa.. refreshing ga untundi

Open ayyaya

[Dippindots]

cry for sometime

you will feel better

[afacc123]

1 hour ago, Manikyam said:

maradal iste aa chweetness verabba

enduku ivvad

just talk mode loki teste chaalu