Jump to content

Looks like another covid drug scam, this time with DRDO stamp. #2DG


Recommended Posts

  • Raven_Rayes changed the title to Looks like another covid drug scam, this time with DRDO stamp. #2DG
Posted

https://science.thewire.in/the-sciences/dr-reddys-doc-vidya-webinar-2-dg-clinical-trials-primary-endpoints-problems/

 

The Wire Science had earlier explained how 2-DG’s approval was based on evidence that wasn’t there. A short recap follows.

Preclinical data – DRDO first presented some data to suggest 2-DG may inhibit the growth of the novel coronavirus in groups of cells cultured in the laboratory, with no indication that 2-DG would have the same effect in humans, a vastly more sophisticated collection of cells.

Clinical data – Both phase 2 and phase 3 trials for 2-DG had a common flawed design. They measured patients’ outcomes on a subjective scale (such as scoring some aspects of their improvement on a scale of 1-10 scale). The common advice when using such subjective endpoints is to blind the trial: to ensure the doctors administering the trial don’t know who received the treatment (2-DG) and whom the placebo. However, neither trial had such blinding either.

As a result the results are deemed at the outset to be much less reliable than is typically expected from human clinical trials involving vaccines.

In addition, we already know several drugs – ivermectin, hydroxychloroquine, chloroquine, doxycycline, azithromycin and lopinavir – inhibited virus growth in the lab but failed human clinical trials. This rendered the need for, and the absence of, a good clinical trial more problematic.

Also read: Lack of Definitive COVID-19 Treatment

Posted
18 minutes ago, astalavistaa said:

I know that this is coming. this country has gone bonkers @~`

292494234_tenor(2).thumb.gif.1f93201d40a

Join the conversation

You can post now and register later. If you have an account, sign in now to post with your account.

Guest
Reply to this topic...

×   Pasted as rich text.   Paste as plain text instead

  Only 75 emoji are allowed.

×   Your link has been automatically embedded.   Display as a link instead

×   Your previous content has been restored.   Clear editor

×   You cannot paste images directly. Upload or insert images from URL.

×
×
  • Create New...