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Biochemists at the University of Wisconsin鈥揗adison have create [url=https://www.nikeairforces.de]air force1[/url] d the first atlas that maps where molecular tools that can switch genes on and off will bind to the human genome. It is a development they say could enable these tools to be targeted to specific parts of an individual鈥檚 genome for use in precision medicine, developing therapies and treating disease.The study is published in the Proceedings of the National Academy of Sciences. The tools are polyamides, engineered DNA-binding molecules that are an important component of artificial transcription factors. Transcription factors 鈥?both [url=https://www.adidas-yeezy.it]yeezy 700[/url] natural and artificial 鈥?determine which genes are translated into proteins inside cells.鈥淲e know that transcription factors bind to specific sites in the genome and when they mis [url=https://www.dunks.fr]dunk femme[/url] fire they drive many diseases, including cancers,鈥?explains lead study author Graham Erwin, a former graduate student in the lab of Aseem Ansari, a professor in the Department of Biochemistry and the Genome Center of Wiscon RAWALPINDI:Robbers have struck at a house and made off with cas [url=https://www.nbbalance.es]nb mujer[/url] h and valua [url=https://www.nbbalance.fr]newbalance 990[/url] bles worth millions of rupees within the airport police jurisdiction. Mohammad Naseer, a resident of Nazeerabad, lodged a complaint with the local police stating that four robbers barged into his house, held his family hostage at gunpoint and made off [url=https://www.nbbalance.es]nb 9060[/url] with Rs200,000 in cash, prize bonds, 13 carats of gold, five cell phones and other valuables worth Rs800,000. The police have registered a case, but no recoveries or arrests had been till the filing of this report.Published in The Express Tribune, May 13th, 2016.

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EpiCypher has announced the award of five grants for Histone Peptide Array Screening Services to researchers at Indiana University, Memorial Sloan Kettering Cancer Center, The University of Florida, The University of Montreal and The Structu [url=https://www.nbbalance.de]nbbalance[/url] ral Genomics Consortium as par [url=https://www.yeezyy.at]yeezy[/url] t of their first annual grant program in support of chromatin biology and epigenetics researc [url=https://www.nike-dunks.de]nike dunk sb [/url] h.The scientific founders of EpiCypher reviewed each grant application and selected the winners, each of whom will receive histone modification screening services employing EpiCypher鈥檚 world-class EpiTitan鈩?Histone Peptide Arrays, along with a statistical analysis of their protein鈥檚 or antibody鈥檚 histone modification binding profile.The grantees are: Levi Blazer, Ph.D., Structural Genomics Consortium; El Bachir Affar, Ph.D., University of Montreal; Omar Abdel-Wahab, M.D., Memorial Sloan-Kettering Cancer Center; Feng-Chun Yang, Ph.D., Indiana University School of Medicine; and Daiqing Liao, Ph.D, University of Florida.The grant r ISLAMABAD:Enhancing the country鈥檚 exports and achieving its trade targets is the ultimate priority of the government, remarked Federal Minister for Commerce and Textile Pervez Malik on Wednesday.Talking to APP, he emphasised that he would frame short, medium and long-term strategies for enhancing trade with different partner-countries across the world.Commenting on trade relations with the European Union, Malik said Pakistan had a major opportunity to gain a greater market share due to the leverage provided by the Generalised Scheme of Preferences (GSP) [url=https://www.nbbalance.es]nb balance[/url] Plus status.鈥淓xports of home textile products from Pakistan to the EU increased 60% in 2016 compared to 2013,鈥?he said in reply to a question.The minister said Pakistan鈥檚 exports of carpets and rugs to the EU rose from 30.3 million euros in 2013 to 37.92 million euros in 2016.Potential exists to boost bilateral [url=https://www.adidascampus.com.de]adidas campus 80s[/url] tradeExports of cotton and other raw material f [url=https://www.campusadidas.fr]adidas campus grise[/url] or value-added textiles grew rather modestly by about 9% in 2016 compared to 201

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An important goal of early-phase clinical trials is to discover a drug鈥檚 possible side effects. But despite FDA guidelines seeking to standar [url=https://www.adidas-yeezy.it]Scarpe Yeezy[/url] dize this reporting, a University of Colorado Cancer Centerstudyfinds significant variation in how drug side effects are reported, potentially making some drugs seem safer or less safe than they really are. 鈥淲ithout standardizing how we present such data, there is the potential for misinformation about these side effects,鈥?[url=https://www.nikeairforces.de]air force1[/url] sa [url=https://www.yeezyy.at]yeezys kaufen[/url] ys Emily Simons, MD, MPH, senior resident at University of Colorado School of Medicine and the first author of the study.The group including senior author D. Ross Camidge, MD, PhD, got interested in the topic after seeing how differently the side effects of new drugs for treating lung cancer were being presented 鈥?and realizing that differences in reporting methods could over- or under-estimate the apparent safety of such drugs. 鈥淪ometimes you only report an adverse event that happens in, say, 10 percent or more of patients on KARACHI:K-Electric鈥檚 profit increased 16% to Rs32.75 billion in the year ended June 3 [url=https://www.valela.at]ugg boots damen[/url] 0, 2017 on the back of higher self-generation at a reduced fuel cost and lower financ [url=https://www.adidas-samba-adidas.it]adidas samba uomo[/url] e cost, according to a bourse filing on Wednesday.The integrated power company had posted a profit of Rs28.32 billion in the previous year.Accordingly, its earnings per share (EPS) rose to Rs1.19 in FY17 from Rs1.03 in the previous year.K-Electric is a listed firm at the Pakistan Stock Exchange. Its share price increased 2% or Rs0.14 to Rs7.05 with a volume of 14.75 million shares.K-Electric announces fresh $1-billion investmentThe [url=https://www.adidascampus.com.de]adidas campus beige[/url] company reported to the PSX that it purchased electricity worth Rs54.30 billion from the national grid station and independent power producers in FY17. This was 24% lower than the Rs71.48 billion paid to the power sellers last year.Similarly, it consumed fuels worth Rs57.26 billion compared to Rs59.95 billion in the previous year.The drop in the value of purchased power and fuel consumption

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In a new study that could improve the therapeutic efficacy of deep-brain stimulation (DBS) for psychiatric disorders such as depression, a team of scientists shows that, when DBS is applied to a specific brain region, it improves patients' cognitive control over their behavior by increasing the power of a specific low-frequency brain rhythm in their prefrontal cortex.The findings, published April 4 in Nature Com [url=https://www.adidas-yeezy.it]adidas yeezys[/url] munications, suggest that the increase in "theta" rhythms, readily detectable in EEG recordings, could provide neurosurgeons and psychiatrists with the reliable, objective and rapid feedback they've needed to properly fine-tune the placement and "dosage" of DBS electrical stimulation. In Parkinson's disease, where DBS has been most successful, that kind of feedback is available through a reduction in a patien [url=https://www.nbbalance.de]nb sneakers 574[/url] t's tremors. But for depression or obsessive-compulsive disorder [url=https://www.nikeairforces.de]air forceone[/url] , symptoms can be more subtle, subjective and slowly emergent."This is a major step forward for psychiatric b A suicide car bomber killed at least 14 people including women and children packed into a minibus at a checkpoint outside a central Iraqi town on Monday morning, police and hospital sources said.A police officer at the scene said most of the victims died inside their vehicles while waiting to enter Khal [url=https://www.adidassamba.com.de]adidas samba sale[/url] is, about 80 km (50 miles) north of Baghdad.Islamic State suicide bomber kills at least 15 in Baghdad"We still have charred bodies inside many vehicles including a minibus packed with women and children," the police captain said, requesting an [url=https://www.adidascampus.com.de]campus adidas schuhe[/url] onymity.There was no immediate claim of responsibility, but Islamic State militants have stepped up attacks even as they incur battlefield setbacks in northern and western Iraq.Hospital sources said the death toll was expected to rise given the extent of critical injuries.Amid mourning: Baghdad bombing toll goes up to 213Iraqi Prime Minister Haider al-Abadi has come u [url=https://www.nbbalance.fr]newbalance 530[/url] nder pressure to improve security since a suicide attack claimed by Islamic State e

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Rsfz Whole Genomes of Individuals Dated to the Three Kingdoms Period of Korea Sequenced
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Yick Attock Refinery s earnings rise four times in 1H
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Fzwc Turkish border guards fire on fleeing Syrians, 8 dead
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Otcr Peshawar Institute of Cardiology: Court stays decision to place cardiology institute under LRH BoG
LabAutomation2008 has welcomed 4,670 registrants from 40 countries around the world to the Palm Springs Convention Center, Palm Springs, CA, January 26-30.LabAutomation2008 continued a tradition of delivering high-quality education and innovation. The conference featured the top 100 podium presentations on laboratory automation, which were organized in five educational tracks, 18 short courses, 189 poster presentations, 33 academic travel awards and 21 industry-sponsored workshops. The exhibit portion of [url=https://www.adidas-yeezy.it]yeezy foam[/url] LabAutomation2008 included more than 50 new products, and 242 exhibitors in 420 booths. 鈥淚t is truly exciting to be a part of LabAutomation2008 and this scientific society that drives education and innovation in laboratory science,鈥?said ALA President Jim Sterling, Ph.D. and Professor at Keck Graduate Ins [url=https://www.nbbalance.de]new balances 480[/url] titute.鈥淓verything about this conference and exhibit underscores this statement. The plenary ses [url=https://www.adidas-yeezys.fr]baskets yeezy[/url] sions, short courses, industry-sponsored workshops, podium presentations and posters all ISLAMABAD/KARACHI:The Muttahida Qaumi Movement (MQM) moved on Wednesday to propose a shadow budget, suggesting an outlay of Rs4.5 trillion and urging the federal finance minister to include local governments鈥?suggestions in an effort to make the upcoming budget 鈥榩eople-friendly鈥?Party MNA and senior deputy convener Dr Farooq Sattar discussed the sal [url=https://www.nbbalance.fr]new balance 740[/url] ient features of the shadow budget, prepared by MQM鈥檚 Economic and Finance Committee, and said: 鈥淚shaq Dar should t [url=https://www.stanley-cup.us]stanley products[/url] ake suggestions from KMC, LMC and other local governments and include people at grassroots level.鈥滿QM presents shadow budget worth Rs668bThe event, attended by businessmen, diplomats and technocrats, was hosted by the p [url=https://www.adidas-samba-adidas.fr]adidas samba og[/url] arty at Beach Luxury Hotel.According to MQM鈥檚 estimates, the government鈥檚 budget outlay 鈥渨ill be around Rs4.8 trillion鈥?Sattar said: 鈥淥ur proposals call for decreased sales tax, lowering it to a single digit.鈥滿QM鈥檚 proposals also included raising minimum wages to Rs20,000 in addition to a 15 percent increase in pe

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Tibi Thermo Fisher Scientific Completes Acquisition of One Lambda
Clinical Data, Inc. has announced that the Company will begin enrollment of a pivotal Phase III clinical trial for vilazodone, a compound being studied for treatment of depression, and anticipates having initial results from this study available by mid-2007. The outcome of this [url=https://www.adidas-yeezys.fr]adidas yeezy[/url] trial would serve as one of two pivotal trials required for a new drug application ("NDA"), which the Company hopes to file with the United States Food & Drug Administration as early as year end 2008. Carol R. Reed, M.D., the Company's Chief Medical Officer, said, "Following our recent meeting with the staff of the Division of Psychiatry Products of the FDA we are accelerating our dev [url=https://www.nikeairforces.de]nike air force 1[/url] elopment plans for vilazodone and a companion biomarker test.""We believe this program has the potential to revolutionize the treatment of depression. As part of this trial, Clinical Data will use its expertise in biomarker discovery to identify biomarkers for response to vilazodone.""We plan to use [url=https://www.adidas-yeezys.es]yeezy[/url] these biomarkers to develop a tes KARACHI:The wait is over! The tra [url=https://www.campusadidas.it]campus adidas[/url] iler of the Alia Bhatt and Varun Dhawan-starrer Badrinath Ki Dulhania is finally out and we are love-struck. An entertaining mix of drama, emotion, comedy and various flavours of love, the three-minute-long trailer will make you fall in love with Alia-Varun鈥檚 sizzling chemistry.Alia plays the role of a practical college student and Varun takes on the role of a hopeless romantic who's impatient to get married.My aim is to make films everyone can enjoy: Varun DhawanFeaturing two confused love birds, the trailer shows Varun stalk [url=https://www.adidascampus.com.de]adidas campus wei脽[/url] ing Alia in the first still and as typical 鈥榙esi romance鈥?goes in almost every Karan Johar directorial, the duo is seen dancing together to festive songs in the following scene.There鈥檚 a twist in the story when Alia begins to reciprocate the love, and we notice that both characters are poles apart. While Varun鈥檚 life revolves around love, Alia [url=https://www.stanley-cup.com.de]stanley kaufen[/url] holds dignity in high regard.Have something to add to the story? Share it in the comments

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