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The new technique holds the promise of a potent new tool to offset the growing challenge of antibiotic resistance by bacterial pathogens, according to the team.Individual DNA bases can be chemically modified, with significant functional consequences. In the bacteri [url=https://www.adidas-yeezys.fr]yeezy sandales[/url] al kingdom, the most prevalent base modifications are in the form of DNA methylations, specifically to adenine and cytosine residuals. Beyond their participation in host defense, increasing evidence suggests that these modifications also play important roles in the regulation of gene expression, virulence, and antibiotic resistance.The research team employed the PacBio庐 RS II system, which can collect data on base modifications simultaneously as it collects DNA seq [url=https://www.jordann.at]jordan2[/url] uence data. The instrument鈥檚 single molecule, real-time sequencing enables the detection of N6-methyladenine [url=https://www.adidas-yeezys.fr]adidas yeezy[/url] and 4-methylcytosine, two major types of DNA modifications comprising the bacterial methylome. However, existing methods for studying bacterial methylomes re LONDON:Ryan Giggs has rejected an offer to stay at Manchester United and is ready to end his association with the club after 29 years, a British newspaper reported on Thursday.Giggs, who played 963 times for United after joining the club as a 14-year-old, worked as a coach under David Moyes and Louis van [url=https://www.nbbalance.it]newbalance scarpe[/url] Gaal.But the Daily Mail said he has decided against taking up an offer of a reduced role from new manager Jose Mourinho.Manchester Uni [url=https://www.nbbalance.es]new balance327[/url] ted appoint Jose Mourinho as manager"Giggs' representatives are now in negotiations with United over a pay-off for the final year of h [url=https://www.adidas-samba-adidas.it]adidas samba donna[/url] is contract," the Mail said.It was reported that Giggs has not spoken directly to Mourinho, who starts work at United on Monday.Manchester United sack Van GaalGiggs is likely to be questioned about his future on British television on Thursday when he starts work as an ITV pundit ahead of the Euro 2016 quarter-final between Poland and Portugal.The Welshman had been tipped as a future Manchester United manager, but is now ex

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LAHORE:An anti-terrorism court (ATC) granted post-a [url=https://www.yeezy.com.mx]yeezy boost[/url] rrest bail to eight accused involved [url=https://www.dunks.fr]dunk sb[/url] in the case of attacking Askari [url=https://www.adidas-yeezy.de]yeezys kaufen[/url] Tower during the May 9 violence. President聽 of the Islamabad Chamber of Commerce and Industry (ICCI) Zafar Bakhtwari, while addressing the Federation of Pakistan Chamber of Commerce and In [url=https://www.nikeairforces.de]nike air forces[/url] dustry (FPCCI), said on Monday that businessmen should be given due representa [url=https://www.inkwiz.se]ugg boots tasmania[/url] tion in government decision-making bodies for formulating business-friendly economic policies. Bakhtwari made the remarks while leading an ICC [url=https://www.jordann.at]jordan2[/url] I delegation during a meeting with FPCCI President Haji Fazal Kadir Khan Shirani. Bakhtawari urged the government to build the confidence of businessmen by ensuring supply of basic ingredients that are required to pull the wheel of economy and acceleration of trade and investment in the country.Published in The Express Tribune, March 12th, 2013.Like Business on Facebook to stay informed and join in the conversation.

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RAWALPINDI:Chief of Army Staff (COAS) General Syed Asim Munir visited forward areas along the Line of Control (LOC) on Thursday, said a statement by the Inter-Services Public Relations (ISPR).On the occasion, General Munir was briefed on the secu [url=https://www.adidas-yeezy.it]yeezy[/url] rity situation and the operational preparedness of the deployed formations.He also met with officers and troops stationed at the forward positions.The COAS emphasised upon troops to extend all-out support to the local p [url=https://www.dunks.fr]nike air dunk[/url] opulation, remain steadfast and discharge duties with utmost sincerity and devotion, added the ISPR.Read COAS lauds courage of troops participating in ongoing fight against terrorHe appreciated the officers and soldiers for maintaining continued vigil, remarkable operational preparedness and a high state of morale.He further said that the Pakistan Army is resolved to defend the sovereignty and terri [url=https://www.nike-dunk.es]nike dunk sb[/url] torial integrity of Pakistan against all kinds of threats and is determined to support the just cause of Kashmiris and seeks resoluti KARACHI:Mahin Hussain s love [url=https://www.yeezyy.at]yeezy 350[/url] affair with bags has lasted 10 years, and is still going strong. A [url=https://www.valela.at]ugg boots damen[/url] n IVS grad from the batch of 2002, she speaks earnestly to The Express Tribune about her vision, It was to be different. A road less travelled, one that has not been taken before. It was indeed the one she took, opting to design accessories rather than become a run-of-the-mill apparel designer.Of her unusual choice, she says, I wanted to do something missing from the market, something off-beat. I felt I needed to stand out from the crowd. Back in 2003, she first started making samples of screen-printed fabric bags out of her house, where she had a tiny workshop. Hussain later attended the London [url=https://www.adidascampus.com.de]adidas campus adv[/url] College of Fashion, graduating in 2007 with a diploma in Fashion Accessories. It was here, she recalls, that her understanding of the craft grew. It was a very hands-on course, [including] bag making in leather, [ranging] from pouches to belts. It showed me that I could work in a new medium. Upon he

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RAWALPINDI:The SHO of Rawalpindi 39;s Women 39;s police station, Inspector Irum Khanum, has been removed from her post and [url=https://www.dunks.fr]nike dunk dunk[/url] transferred following an investigation into accusations of theft and blackmail.The inquiry, conducted by the Rawalpindi Regional Investigation Branch, focused on accusations involving the theft of money from a complainant 39;s purse and allegations of blackmail against SHO Irum Khanum by a lady muhrir named Anita Naseem.The probe revealed that the accuser, Anita, had already been dismissed. Despite the completion of the inquiry, allegations of the complainant 39;s relationship with the constable could not be substantiated.The conflict between SHO Irum Khanum and Lady Constable Anita Naseem came to light last month, prompting an investigation by the SP Headquarters Rawalpindi. The inquiry found Lady Muharar Anita Naseem guilty, resulting in her dismissal from the job.ReadNew [url=https://www.adidas-yeezy.de]adidas yeezy boosts[/url] scandal hits women rsquo;s police stationC [url=https://www.nike-dunk.it]nike dunk panda[/url] CTV footage from the police station surfaced, FAISALABAD:Five prisoners escaped on Monday night when armed assailants attacked a police van carrying prisoners on Faisalabad-Okara Road. Police said three policemen, including a head constable, were injured in the incident. Constables Muha [url=https://www.campusadidas.it]adidas campus 80s[/url] mmad Parvaiz, Muhammad Bashir (driver) and Constable Muhammad Noor had been taken to divisional headquarters hospital where their condition was reportedly out of danger. Police said the vehicle carrying eight prisoners involved in robberies was on its back from Faisalabad when it was attac [url=https://www.nikeairforces.de]nike af[/url] ked near Mari Pattan. Police said the assailants approached the van on a car and a motorcycle and opened fire at it. The prisoners who escaped were indentified as Abrar Shah, Sarfaraz Shah, Muhammad Asif, Asif Ahmad and Muhammad Asif. Faisalabad City Police Officer (CPO) Haidar Ashraf and the Okara SSP [url=https://www.nikeairforces.de]air force beige[/url] are jointly supervising the team formed to trace the criminals.Published in The Express Tribune, December 4th, 2013.

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Niir HED promotes 723 female college lecturers
BAHAWALPUR:Punjab Chief Conservator Forest Extension Faisal Haroon Friday visited Lal Sohanra National Park, some 30 kilometres from the city and inspected the flowers nursery and progress of different development projects.Forest Bahawalpur [url=https://www.nike-dunk.it]nike dunk nera[/url] Conservator Saeed Tabassum briefed him about PM s Ten BIllion Tree Tsunami project.The chief conservator directed to plant more trees under the project and achieve the set targets. He visited nursery set up for Ten Billion Tree Tsunami pr [url=https://www.adidas-yeezys.fr]yeezy bleue[/url] oject and directed to ta [url=https://www.dunks.fr]dunk sb[/url] ke special care of plants and saplings.He also appreciated flora and fauna of Lal Sohanra National Park.Published in The Express Tribune, May 2nd, 2020. Miratul Uroos, written by Nazir Ahmed Dehlvi in the 1830s, was one of the first fictional novels that talked about female literacy in the Indian subcontinent. It is a story of two Muslim sisters from Delhi having two very different lives. Akbari is depicted as a useless evil character, without an ounce of goodness in her, whereas Asghari is presented as an angel without a streak of mal-intent. Though the novel was on the important issue of female literacy, its extreme depiction of the two characters was criticised [url=https://www.adidas-samba-adidas.fr]adidas samba verte[/url] for being unrealistic. How times have changed, for now we are becoming a nation that views others as either an Akbari or an Asghari . If someone is bad , he/she can never be good and if something or [url=https://www.stanley-cup.com.de]stanley[/url] someone is good , it is impossible for them to be corrupt in any way. Either Malala is a n [url=https://www.adidas-samba-adidas.it]adidas samba rosse[/url] ational hero or a national disgrace. We are becoming a people who have learned to live on either side of extreme positions and are proud of it.This Akbari / Asghari mentality has o

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Gjus Delaying verdict Dr Shakil Afridi case hearing adjourned
DIJKOT:A married woman, a resident o [url=https://www.adidas-yeezys.fr]yeezys slide[/url] f Ghulam Muhammadabad, who taught at a private school in Marzipura was allegedly subject to sexual harassment by the school owne [url=https://www.adidas-yeezy.de]yeezys herren[/url] r and two other me [url=https://www.adidas-yeezy.it]yeezy foam runner[/url] n. ISLAMABAD:As Pakistan formally received the Generalised System o [url=https://www.campusadidas.it]adidas campus fucsia[/url] f Preferences (GSP) Plus status, the government has had to set in motion accompanying conditions to retain the status, including setting up a special working group to track progress on implementation of 27 conventions of the United Nations. Minister of State for Commerce and Textile Industry Khurram Dastgir Khan informed on Tuesday that the聽group, setup in the Foreign Office, will monitor progress on implementation of 27 UN聽conventions. The move has been deemed necessary if聽Pakistan wants to remain eligible to avail the ten-year duty free access to the European Union markets.Addressing a press conference on the technical aspects of the GSP Plus [url=https://www.conversede.de]converse sneakers[/url] , he further shared details of the incentives that the EU had recently granted Pakistan.Pakistan has ratified most of the required UN conventions that mainly pertain to human rights, labour [url=https://www.adidas-samba-adidas.it]adidas samba bianche[/url] rights, women, children, minority rights and freedom of expression.Dastgir said the major chal

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PESHAWAR:Khyber-Pakhtunkhwa Health Minister Syed Qasim Ali Shah has written a [url=https://www.adidas-yeezy.de]yeezy boost[/url] letter to the Punjab chief secretary, expressing c [url=https://www.adidas-yeezys.fr]yeezy 350 noires[/url] oncerns over the health of Bushra Bibi, PTI founder Imran Khan rsquo;s wife.A day earlier, the PTI founder had claimed that his wife had been poisoned while being held at the Bani Gala sub-jail, demanding a medical examination for her by a doctor from Shaukat Khanum Hospital.The letter requested the Punjab government to allow a panel [url=https://www.yeezy.com.mx]adidas yeezy[/url] of doctors, including specialists from K-P, for the detailed examination of Bushra Bibi, adding that the check-up would confirm or refute the supply of poisonous food. ISLAMABAD:Kainat Riaz, one of the schoolgirls injured in the Taliban attack on Malala Yousafzai, spoke to The Express Tribune about how she remains affected by her attack, but adds that her life is gradually returning to normalcy.Perhaps fearing for her safety, she refuses to comment on who attacked her, but admits the incident has badly affected her life. She cited her constant police escort as one example of how her life is forever altered. I was an ordinary girl and used to visit my grandmothers and other relatives but now I am not allowed to move freely anymore. Because of this fear, I slee [url=https://www.nikeairforces.de]air force beige[/url] p with my mother, Kainat told The Express Tribune in an interview at her home in Swat. A team of police g [url=https://www.asicsgel.de]asic gels[/url] uards have been deployed at her residence since the October attack, who also escort her when she goes to school. I could not sleep for several nights after [url=https://www.valela.at]ugg boots[/url] the incident, said Kainat. She addressed her injury as well, saying, The injury was severe in the beginning. I am ok now after the trea