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The team, led by Melissa Rolls, an assistant professor of biochemistry and molecular biology at Penn State, has found that a mutation in a single gene can entirely shut down the process by which axons -- the parts of the nerve cell that are responsible for sending signals to other cells -- regrow themselves after being cut or damaged. "We are hopeful that this discovery will open the door to new research related to spinal-cord and other neurological disorders in humans," Rolls said. The journal Cell Reports published an early online copy of the paper today (Nov. 1), and also will include the paper in the monthly issue of the journal, which will be published Nov. 29.Rolls explained that axons, which form long bundles extending out from nerve cells, ideally survive throughout an animal's lifetime. [url=https://www.nike-dunk.es]nike store dunk[/url] To be able to survive, nerve cells need to be resilient and, in the event of injury or simple wear and tear, some [url=https://www.nike-dunk.es]nike dunk low[/url] can repair d [url=https://www.nike-dunk.es]dunk nike low[/url] amage by growing new axons. Earlier research from Rolls and others LAHORE:A large portion of the no [url=https://www.stanley-cup.com.de]stanley-cup[/url] n-salary budget (NSB) allocated for schools in fiscal year 2016-17 is released less than half a month prior to the announcement of the budget for the next financial year, The Express Tribune has learnt.According to a notification issued by the Punjab Education Sector Reform Programme (PMIU), Rs8.39 billion had been issued for NSB of schools in 36 districts of the province.The statement was released to inform all Chief Executive Officers (CEOs) of the District Education Authorities (DEAs) of the province. The notification was issued on May 12, [url=https://www.inkwiz.se]ugg ultra mini[/url] just a few days prior to the announcement of Punjab budget for the fiscal year 2017-18, scheduled to be announced on Friday (today).The Rs8.39 billion is part of the Rs14 billion allocated in the budget of fiscal year 2016-17 and makes up around 59.92% of the t [url=https://www.adidas-samba-adidas.fr]adidas sambarose[/url] otal amount allocated for the whole fiscal year. The Punjab Finance Department had only disbursed Rs5.61 billion and the rest was released just days prior to
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Aodj North Korea denies cyber attacks on South Korea officials
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Zvqm Crowdsourced Algorithms Predict Epileptic Seizures
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Agww National Children s Leukemia Foundation Endorses Missouri Stem Cell Research and Cures Initiative
Cangene Corporation has announced the signing of a definitive agreement under which Emergent BioSolutions ("Emergent") of Rockville, Maryland will acquire Cangene in an all-cash transaction valued at US$222 million (approximately C$236 million).Under the terms of the agreement, which has been approved by the Boards of Directors of both companies, Cangene shareholders will receive US$3.2 [url=https://www.adidas-yeezy.de]yeezy[/url] 4 per share (C$3.44 per share) in cash. The purchase price represents a premium of approximately 27% to Cangene's closing stock price of C$2.70 on December 10, 2013 and 45% to Cangene's 90-day volume weighted average stock price.The acquisition will be implemented through a court-approved Plan of Arrangement under Canadian law and is subject to the approval of Cangene common shareholders, court approval and U.S. regulatory approvals and other customary closing conditions. The transaction is expected to be completed in the first calendar quarter of [url=https://www.nbbalance.de]new balances 530[/url] 2014.John Sedor, President [url=https://www.dunks.fr]nike store dunk[/url] and CEO of Cangene, said: "Thi ISLAMABAD:International Telecommuni-cation Union (ITU) Secretary Gener [url=https://www.nbbalance.it]new balance uomo[/url] al Houlin Zhao has announced that his organisation is looking to sponsor more professional training programmes in Pakistan in an effort to further develop capacity of the telecom sector.Zhao was speaking at the inaug [url=https://www.adidas-samba-adidas.es]adidas samba blancas[/url] ural session of the ITU-PTA Asia-Pacific Regulators Roundtable and the ITU-PTA International Training Programme (ITP) 2016 that started on Monday.The event was organised by the Pakistan Telecommunica-tion Authority (PTA) and ITU and attended by representatives of more than 20 countries from the Asia-Pacific r [url=https://www.adidas-samba-adidas.es]adidas samba adidas[/url] egion.He said the roundtable of regulators had particular importance as it was the first symposium in the region since the United Nations General Assembly adopted the Sustainable Development Goals (SDGs), also referred to as the 2030 Agenda for Sustainable Development.鈥淚CTs (information and communication technologies) are the foundation upon which economic and social development can grow. ICTs have an
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Mfhn Brexit may not push Scots towards independence, survey suggests
An experimental treatment developed from cattle plasma for Middle East respiratory syndrome (MERS) coronavirus infection shows broad potential, according to a small clinical trial led by National Institutes of Health scientists and their colleagues. The treatment, SAB-301, was safe and well tolerated by healthy volunteers, with only minor reactions documented.The first confirmed case of MERS was reported in Saudi Arabia in 2012. Since then, the MERS coronavirus has spread to 27 countries and sickened more than 2,000 people, of whom about 35 percent have died, according to the World Health Organization. There are no licensed treatments for MERS.SAB-301 was developed by SAB Biotherapeutics of Sioux Falls, South Dakota, and has been successfully tested in mice. The treatment comes from so-called 鈥渢ranschromosomic cattle.鈥?These cattle have genes that have been slightly altered to enable them to produce fully human antib [url=https://www.nike-dunks.de]dunks nike store[/url] odies instead of cow ant [url=https://www.yeezy.com.mx]tenis yeezys[/url] ibodies against killed micr [url=https://www.nike-dunks.de]nike dunk nike[/url] obes with which the TEHRAN:Iran has failed to reach agreement with Saudi Arabia on arrangements for its pilgrims to join the annual Hajj in September following the severing of ties, its culture minister said on Thursday.An Iranian delegation held four days of talks in Saudi Arabia last month aimed at thrashing out a deal but with Saudi diplomatic missions in Iran closed since January and Iranian flights [url=https://www.stanley-cup.us]stanley website[/url] to the kingdom halted they hit deadlock.Iran-Saudi Hajj talks halted because of visa hurdle"The arrangements have not been put together and it's now too late," Ali Jannati told the official IRNA news agency. "The sabotage is coming from the Saudis.""Their attitude wa [url=https://www.adidassamba.com.de]adidas samba rose[/url] s cold and inappropriate. They did not accept our proposals concerning the issuing of visas or the transport and security of the pilgrims.""Saudi officials say our pilgrims must travel to an [url=https://www.stanleycups.fr]stanley[/url] other country to make their visa applications."Iran has been insisting that Saudi Arabia issue visas through the Swiss embassy in Tehran, which has looked a
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Qyhr Pakistan lose tennis final to Turkey
Olympus Canada Inc. and Hitachi High-Technologies Canada have announced a new partnership makin [url=https://www.dunks.fr]dunk nike store[/url] g Olympus the exclusive distributor of the new TM3000 Table Top Scanning Electron Microscope (SEM) in Canada.Olympus and Hitachi have a long history in Canada for providing quality imaging products and solutions to the laboratory and Research markets. This new generation in fully鈥揳utomated, table-top SEM, with its achievement of 30,000X magnification, depth of field, ease of use, compact size, make it the perfect complement to the Olympus portfolio of optical microscopes and digital cameras.The TM-3000 provides a imaging solution to lab technicians and researchers who require an [url=https://www.adidas-yeezy.it]ciabatte yeezy[/url] imaging system that reaches beyond the range of the light microscope. Requiring no special EM technical skills or sample preparation te [url=https://www.adidas-yeezy.it]yeezys[/url] chniques due to variable pressure, the TM-3000 can be used by anyone able to use a consumer digital camera; it鈥檚 that easy!The TM3000 offers an improvement in all the features of the e FAISALABAD:The Water and Power Development Authority (WAPDA) is all set to construct a dam in Chiniot, some 100 meters upstream of existing railways bridge on River Chenab.Officials told The Express Tribune the homogenous earthfill dam will be 55 feet in height and will have 1.0 MAF live storage capacity of water. In addition, it would also help in producing 69 megawatts of electri [url=https://www.valela.at]ugg[/url] city that would be added to the national grid.China to invest $50b to develop Indus River CascadeThey revealed that Rs136.724 million were spent on the preparation of the feasibility report of the dam and it would be constructed in four years time. They said the project was initially identified [url=https://www.adidas-samba-adidas.it]adidas samba uomo[/url] about two decad [url=https://www.stanley-cup.com.de]stanley shop[/url] es ago; however the formal feasibility was conducted in March 2015.The project was approved by the Central Development Working Party (CDWP) and its funding will be provided by WAPDA and the Public Sector Development Programme (PSDP). While speaking to The Express Tribune, a WAPDA spokesman said, 鈥淭his pr
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Durg MorphoSys to Present Data on Proprietary Programs at 20th Congress of EHA
The study, funded by the Biotechnology and Biological Sciences Research Council (BBSRC), Leverhulme Trust and UCL Chemistry, shows how DNA can be used to build stable and predictable pores that have a defined shape and c [url=https://www.yeezy.com.mx]chanclas yeezy[/url] harge to control w [url=https://www.yeezyy.at]yeezys kaufen[/url] hich molecules can pass through the pore and when.Lead author, Dr Stefan Howorka (UCL Chemistry), said: 鈥淣atural biological pores made of proteins are essential for transporting cargo into and out of biological cells but they are hard to design from scratch. DNA offers a whole new strategy for constructing highly specific synthetic pores that we can open and close on demand. We鈥檝e engineered our pores to act like doors 鈥?the door unlocks only wh [url=https://www.adidas-yeezy.it]yeezy slide[/url] en provided with the right key. By building these pores into drug carriers, we think it will allow for much more precise targeting of therapeutics.鈥滿any therapeutics including anti-cancer drugs can be ferried around the body in tiny carriers called vesicles which are targeted to different tissues using biologica One doesn鈥檛 usually see royalty when t [url=https://www.campusadidas.it]adidas campus bianche[/url] ravelling on the London Underground but the ruler of Dubai and his son recently became exceptions to this rule.Despite having billions in the bank, the Dubai royalty decided on the [url=https://www.adidas-samba-adidas.it]adidas samba donna[/url] rather low-key travel [url=https://www.adidas-samba-adidas.fr]adidas samba beige[/url] option of the London Underground on a visit to the British capital. PHOTO: FACEBOOK
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Ahxm Uruguay losing hope for 22 missing from sunken South Korea ore carrier
The DNA Repair Company (DNAR), an emerging company focused on personalized approaches [url=https://www.nike-dunk.es]nike dunk[/url] to cancer treatment, announced the licensing of the exclusive rights in North America for the use of a newl [url=https://www.nike-dunks.de]nike store dunks[/url] y discovered diagnostic test that strongly predicts how women with breast cancer will respond to a common form of chemotherapy. The rights to the test were acquired from Helsinki University Central Hospital through Licentia Ltd.The discovery, published in this month鈥檚 edition of Nature Genetics, marks an important step toward the development of the first tests capable of identifying the breast cancer patients who should be given an alternative to standard anthracycline-containing chemotherapy regimens.The research teams reporting the discov [url=https://www.nikeairforces.de]air force[/url] ery were led by Dr. Heli Nevanlinna at Helsinki University Central Hospital, Finland and Dr. Jiri Bartek at the Danish Center Society in Copenhagen, Denmark.The test has the promise of guiding oncologists in critical treatment choices. DNAR will utilize the gen KARACHI:Dr Asim Hussain, the Pakistan Peoples Party Karachi division president and a clos [url=https://www.adidas-samba-adidas.es]adidas samba adidas[/url] e aide of former president Asif Ali Zardari, will have to stay in the country to face criminal and corruption trials, at least for now, as the Sindh High Court (SHC) threw out on Monday his petition seeking the return of his Pakistani and Canadian passports and direction for the interior ministry to remove his name from the Exit Control List (ECL).A two-judge bench, headed by Justice Muhammad Junaid Ghaffar, announced its verdict, which was reserved on [url=https://www.nbbalance.es]newbalance 574[/url] May 26, after hearing arguments from the lawyers representing the petitioner, the deputy attorney general and the National Accountability Bureau鈥檚 (NAB) special prosecutor.鈥淚nsofar as the other prayer regarding the memorandum dated November 24, 2015 is concerned, since the name of the petitioner is now placed on the ECL on the basis of an order passed by this court while granting bail to [url=https://www.adidas-samba-adidas.fr]adidas samba verte[/url] the petitioner and which we have maintained by dismissing the m
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Gfmu Vitamin-Filled Gummies Help Vegans and Vegetarians Reach Their RDA
A new antiviral drug that induces mutations in the genetic material of influenza virus i [url=https://www.conversede.de]converse schuhe[/url] s highly effective in treating influenza infection in animals and human airway tissue and could be a groundbreaking advance in influenza therapy, according to a study by theInstitute for Biomedical Sciences at Georgia State University.The antiviral drug blocks RNA polymerase, the enzyme that plays a central role in replicating the genome of influenza virus, causing mutation [url=https://www.adidas-yeezys.fr]yeezy 700[/url] s in the viral genome. If enough mutations occur, the genome becomes nonfunctional and the virus cannot replicate. The findings were published online on Oct. 23 inScience Translational Medicine.鈥淭he compound is highly efficacious against influenza,鈥?said Dr. Richard Plemper, senior author of the study and a professor in the Institute for Biome [url=https://www.adidas-yeezy.it]yeezy slides[/url] dical Sciences. 鈥淚t鈥檚 orally available, it鈥檚 broad spectrum against all influenza virus strains tested, and most important it establishes a high barrier against viral escape from inhibition.鈥? LAHORE:As much as she belonged to the prime batch of models, Tany Shafi was an anomaly of sorts. Fash [url=https://www.nbbalance.es]nb 550[/url] ion [url=https://www.campusadidas.fr]campus adidas[/url] ran in her family and yet, she chose to branch out from being just another fashion model. She ruled the ramp and magazine covers like everyone else but soon transitioned in a TV show host. Silver Screen and a celebrity talk show titled Timeout with Tanya were two of h [url=https://www.nbbalance.it]newbalance 550[/url] er major outings as host. PHOTO: PUBLICITY
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Xnkj First responder initiative launched
A small pilot study shows for the first time that changes in diet, exercise, stress management and social support may result in longer telomeres, the parts of chromosomes that affect aging.It is the first controlled trial to show that any intervention might lengthen telomeres over time.The study was conducted by scientists at UC San Francisco and the Preventive Medicine Research Institute, a nonprofit public research in [url=https://www.adidas-yeezys.fr]yeezy femme[/url] stitute in Sausalito, Calif. that investigates the effect of diet and lifestyle choice [url=https://www.dunks.fr]dunk sb[/url] s on health and disease. The researchers say they hope the results will inspire larger trials to test the validity of the findings.鈥淥ur genes, and our telomeres, are not necessarily our fate,鈥?said lead author Dean Ornish, MD, U [url=https://www.dunks.fr]dunk high[/url] CSF clinical professor of medicine, and founder and president of the Preventive Medicine Research Institute.鈥淪o often people think 鈥極h, I have bad genes, there鈥檚 nothing I can do about it,鈥欌€?Ornish said. 鈥淏ut these findings indicate that telomeres may lengthen to LAHORE:鈥淭erms of reference (ToRs) for the Panama Papers investigation should be finalised in consultation with opposition parties. The prime minister鈥檚 son has confessed to his crime, and an independent investigation should now be launched,鈥?former federal minister Qamar Zaman Kaira said on Sunday.He was addressing a rally organised by the Pakistan Peoples Party (PPP) to mark the International Labour Day. A large number of PPP and labour union workers from WAPDA, Pakistan Railway, PIA, House Building [url=https://www.inkwiz.se]ugg boots[/url] Finance Company and the Civil Aviation Authority attended the rally from Haji Camp to Lahore Press C [url=https://www.campusadidas.fr]adidas campus homme[/url] lub.鈥淲e have confidence in the chief justice but the modus operandi to handle the Panama Papers scandal is not fair,鈥?Kaira said. He said the PPP would oppose what he called Prime Minister Nawaz Sharif鈥檚 attempts to distribute national assets among his friends in the name of privatisation. He said the party would take to the streets if its [url=https://www.stanley-cup.us]stanley cup[/url] demands were not met.Addressing the prime minister,
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Qqvp Three Companies Awarded Funding in Department of Health s SBRI Healthcare Programme
What is treatment-r [url=https://www.nike-dunk.it]dunk nike[/url] esistant depression? New report cal [url=https://www.yeezy.com.mx]yeezy 350[/url] ls for clearer definition to inform research and improve treatment.A group of mental health experts from research, industry, regulatory bodies and with lived experience have proposed new agreed criteria to define the type of depression that current medications and therapies cannot treat effectively. The report aims to provide consistent definitions for future research, and especially for designing clinical trials for new medications, with the aim of helping to develop [url=https://www.nike-dunks.de]nike high dunk[/url] more tailored and effective treatments for people experiencing this difficult condition.Published in Molecular Psychiatry, the report used a well-known method to gain consensus, the Delphi Method, which collected and summarised the views of over 60 experts in the field of depression. The report was led by researchers from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) King鈥檚 College London and National Institute for Health Research (NIHR) Maudsley B With Eid holidays just behind us, the prospects of an anti-government campaign kick-starting soon [url=https://www.adidas-samba-adidas.fr]adidas samba[/url] now loom large. The PTI, which had been at the vanguard of resistance to the ruling PML-N for a long time, had been making loud noises about mounting an anti-PM drive soon after Ramazan. The PML-N鈥檚 foot-dragging on starting an inquiry into allegations unleashed by the Panama Leaks and on the terms of reference for it has been a bone of contention with no consensus being reached on the issue.That was enough to frustrate the opposition and instigate it into protest mode. Already, t [url=https://www.nbbalance.fr]new balance blanche[/url] he PTI, the PPP and the PAT have separately filed disqualification references with the election commission against the prime [url=https://www.nbbalance.it]nb[/url] minister, hoping to exhaust legal options first before taking the next big step. Going by the tone employed by the two sides just before Eid, the omens are not good. Both the PPP and the PTI had been increasingly coordinating their efforts directed against the government. Bilawal Bhutto Zard
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Djkf Vaughan, Martyn celebrate end of pay row with playful banter
Trees are struggling to sequester heat-trapping carbon dioxide (CO2) in warmer, drier climates, meaning that they may no longer serve as a solution for offsetting humanity鈥檚 carbon footprint as the planet continues to warm, according to a new study led by Penn State researchers.鈥淲e found that trees in warmer, drier climates are essentially coughing instead of breathing,鈥?said Max Lloyd, assistant professor of geosciences at Penn State and lead author on the study recently published inProceedings of the National Academy of Sciences. 鈥淭hey are sending CO2 right back into the atmo [url=https://www.adidas-yeezy.it]adidas yeezy[/url] sphere far more than trees in cooler, wetter conditions.鈥漈hrough the process of photosynthesis, tre [url=https://www.yeezyy.at]adidas yeezys[/url] es remove CO2 from the atmosphere to produce new growth. Yet, under stressful conditions, trees release CO2 back to the atmosphere, a process called photores [url=https://www.yeezy.com.mx]yeezy[/url] piration. With an analysis of a global dataset of tree tissue, the research team demonstrated that the rate of photorespiration is up to two times higher in war [url=https://www.nbbalance.fr]new balance pour femme[/url] LONDON:Theresa May was unhappy with the 鈥済ung-ho鈥?approach her predecessor took to Chinese investment in Britain, a former colleague said on Saturday, after the new British prime minister cast into doubt a high-profile Chinese-funded nuclear project. Britain had been due to sign off [url=https://www.nbbalance.it]newbalance 530[/url] on Friday on a plan by France鈥檚 EDF to build two new reactors at Hinkley Point, with financial backing from China General Nuclear (CGN), in a deal championed by David Cameron as a sign of Britain鈥檚 openness to foreign investment. Instead, just hours before the signing ceremony May鈥檚 government announced it would review the project again. Britain and EDF first reached a broad commercial agreement on the Hinkley Point project in 2013 while the Chinese involvement was sealed two years later. The about-turn came little more than a month after Briton [url=https://www.campusadidas.it]adidas campus donna[/url] s voted to leave the EU in a referendum.Published in The Express Tribune, July 31st, 2016.Like聽Business on Facebook, follow @TribuneBiz聽on Twitter to stay informed a
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Allw Punjab to slap ban on import of tyre scrap
Per-/poly-fluroalkyl substances, or PFAS, are everywhere. They are used in firefighting foam, car wax, and even fast-food wrappers. They鈥檙e one of the most toxic substances ever identified鈥攈armful at concentrations in the parts per trillion鈥攜et very little is known about them. PFAS, which is a class of over 3000 compounds, are onl [url=https://www.nikeairforces.de]air forceone[/url] y regulated at the state level, so while some states are working to aggressively tackle the problem, o [url=https://www.adidas-yeezys.fr]yeezy boost[/url] ther states have chosen to ignore PFAS completely, leaving concentrations unknown and health risks unexplored.Tomorrow from 10 a.m. to 2 p.m. EDT at the Geological Society of America鈥檚 2020 Annual Meeting, a technic [url=https://www.jordann.at]nike jordan damen[/url] al session will help bring PFAS to national attention. Presentations will discuss how PFAS are released into the environment, transported through groundwater, river, and soils, and partially remediated. PFAS have been produced in the U.S. for decades, primarily for industrial use. Matt Reeves, a professor at Western Michigan University and lead auth When it comes to Sridevi, adjectives and superlatives begin to pale and fail. In the trailer of her eagerly awaited new film "Mom", she is seen at the peak of her performing power, furnishing an intensity and a heft far beyond wh [url=https://www.nbbalance.es]nb 530[/url] at one expects in a film about the mother-daughter relationship.This [url=https://www.stanleycups.fr]stanleycup[/url] poster of 'Mom' featuring Sajal Aly and Sridevi has sparked our curiosity S [url=https://www.nbbalance.it]newbalance scarpe[/url] CREENGRAB
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Vmfh Advanced Pancreatic Cancer Model Developed
A new drug shows potential to halt cancer cells' growth by stunting the cells' biological clock.The findings from scientists at the USC Michelson Center for Convergent Bioscience and Nagoya University's Institute of Transformative BioMolecules (ITbM) advance a burgeoning area of research: turning the body's circadian rhythms against cancer.Their study, conducted on human kidney cancer cells and on acute myeloid leukemia in mice, was published Jan. 23 in the journal Science Advances.Scien [url=https://www.adidas-yeezy.de]yeezy[/url] tists know that di [url=https://www.adidas-yeezys.com.mx]yeezy[/url] srupting sleep and [url=https://www.nike-dunk.es]dunk nike low[/url] other elements of humans' circadian rhythm can harm health. The same is true for the circadian clock of cells themselves. If researchers could disturb the circadian clock of cancer cells, they theorize, they could potentially hurt or kill those cells.The scientists found that a molecule named GO289 targets an enzyme that controls the cell's circadian rhythm. This drug-protein interaction then disrupts the functions of four other proteins that are important for cell g RAWALPINDI:The Pirwadhai police on Monday arrested thre [url=https://www.stanley-cup.com.de]stanley[/url] e suspected gamblers and seized st [url=https://www.adidas-samba-adidas.it]adidas sambarose[/url] ake money and other valuables from their possession. Acting on a [url=https://www.adidas-samba-adidas.fr]samba og adidas[/url] tip-off, the police raided a gambling hideout and arrested Arsalan, Amir and Javed while gambling on cards. The police also seized Rs19,000 stake money and four litres of liquor.Published in The Express Tribune, July 26th, 2016.
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Untl Technology Reveals Workings of Signaling Proteins in Living Cells
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